DRSC/TRiP Functional Genomics Resources

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Protein Alignment haf and Lgr6

DIOPT Version :9

Sequence 1:NP_001356954.1 Gene:haf / 33339 FlyBaseID:FBgn0261509 Length:1347 Species:Drosophila melanogaster
Sequence 2:XP_573455.1 Gene:Lgr6 / 498233 RGDID:1560339 Length:965 Species:Rattus norvegicus


Alignment Length:367 Identity:111/367 - (30%)
Similarity:163/367 - (44%) Gaps:76/367 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 TTPLLLLLPLILGRLHVAHA-----------QCPWQRDVPDLQTSCICAYNLGRELSVQCDQVDF 67
            ::||||.|.|.:....:|.|           .||         ..|.|..: |..||..|.::..
  Rat     3 SSPLLLALCLCVVLCALARAGSDPQPGPGRPACP---------APCHCQED-GIMLSADCSELGL 57

  Fly    68 SQLLAAMNTHARLKPVDL--------LYVNNSTISELPDAVFSNLS-LHNLQLSSCGIQRIATGA 123
            |::           |.||        |.:||  ::||...:|.:|. |..|:||...:..|...|
  Rat    58 SEV-----------PADLDPLTAYLDLSMNN--LTELQPGLFHHLRFLEELRLSGNHLSHIPRQA 109

  Fly   124 FKGQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQLSHIPDDAFVGLTKLSTLKLNDNN 188
            |.|..| |:.|.||.|.|..:|.|||..|..|..|.|..|.:|.:|:.:|.||:.|..|.|:||.
  Rat   110 FSGLHS-LKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNA 173

  Fly   189 VTLASNAFRGLEQSLKNLNLKGTKQRKVP-ESIRGLKSLAFLDLSQNGIKELPGAGGIRVFDGLD 252
            :|                        ::| .::..|.:|..:.|:.|.|:.:|.    ..|..|.
  Rat   174 LT------------------------EIPVRALNNLPALQAMTLALNRIRHIPD----YAFQNLT 210

  Fly   253 ALTALNLERNLIQSIGETAFAGVRKTLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGFNLLTSLP 317
            :|..|:|..|.||.:|..:|.|:. .|.:|.|..|.|.|||: |:.:|..|:.|....|.:.::|
  Rat   211 SLVVLHLHNNRIQHVGTHSFEGLH-NLETLDLNYNELQEFPV-AIRTLGRLQELGFHNNNIKAIP 273

  Fly   318 EAAFRGNPGITLLALDGNPLSSVPEGAFAHLNATLRGLSLGG 359
            |.||.|||.:..:....||:..|...||.:| :.|..|||.|
  Rat   274 EKAFMGNPLLQTIHFYDNPIQFVGRSAFQYL-SKLHTLSLNG 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hafNP_001356954.1 LRR <52..>252 CDD:227223 58/209 (28%)
leucine-rich repeat 86..105 CDD:275380 6/18 (33%)
leucine-rich repeat 106..129 CDD:275380 8/22 (36%)
LRR_8 131..189 CDD:338972 25/57 (44%)
leucine-rich repeat 131..154 CDD:275380 11/22 (50%)
leucine-rich repeat 155..178 CDD:275380 9/22 (41%)
leucine-rich repeat 179..202 CDD:275380 6/22 (27%)
leucine-rich repeat 203..225 CDD:275380 2/22 (9%)
leucine-rich repeat 226..253 CDD:275380 7/26 (27%)
LRR_8 254..337 CDD:338972 30/82 (37%)
leucine-rich repeat 254..302 CDD:275380 19/47 (40%)
leucine-rich repeat 303..326 CDD:275380 9/22 (41%)
leucine-rich repeat 327..350 CDD:275380 6/22 (27%)
PCC 332..>413 CDD:188093 11/28 (39%)
PRK10927 <1061..>1097 CDD:236797
Lgr6XP_573455.1 LRRNT 34..68 CDD:214470 12/54 (22%)
LRR_RI <70..248 CDD:238064 65/209 (31%)
leucine-rich repeat 70..91 CDD:275380 7/22 (32%)
LRR_8 92..150 CDD:290566 24/58 (41%)
leucine-rich repeat 92..115 CDD:275380 8/22 (36%)
leucine-rich repeat 116..139 CDD:275380 11/22 (50%)
LRR_8 138..198 CDD:290566 20/83 (24%)
leucine-rich repeat 140..163 CDD:275380 9/22 (41%)
leucine-rich repeat 164..187 CDD:275380 8/46 (17%)
LRR_8 186..246 CDD:290566 20/64 (31%)
leucine-rich repeat 188..211 CDD:275380 7/26 (27%)
leucine-rich repeat 212..235 CDD:275380 9/23 (39%)
leucine-rich repeat 236..258 CDD:275380 10/22 (45%)
LRR_RI 253..>442 CDD:238064 22/63 (35%)
LRR_8 258..314 CDD:290566 20/56 (36%)
leucine-rich repeat 259..282 CDD:275380 9/22 (41%)
leucine-rich repeat 283..304 CDD:275380 5/20 (25%)
LRR_8 305..364 CDD:290566 5/10 (50%)
leucine-rich repeat 330..344 CDD:275378
leucine-rich repeat 354..375 CDD:275380
LRR_8 375..434 CDD:290566
leucine-rich repeat 376..399 CDD:275380
leucine-rich repeat 400..421 CDD:275380
leucine-rich repeat 424..444 CDD:275380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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