DRSC/TRiP Functional Genomics Resources

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Protein Alignment haf and lrrc40

DIOPT Version :9

Sequence 1:NP_001356954.1 Gene:haf / 33339 FlyBaseID:FBgn0261509 Length:1347 Species:Drosophila melanogaster
Sequence 2:NP_001011310.1 Gene:lrrc40 / 496765 XenbaseID:XB-GENE-968689 Length:605 Species:Xenopus tropicalis


Alignment Length:305 Identity:89/305 - (29%)
Similarity:127/305 - (41%) Gaps:61/305 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 DQVDFSQLLAAMNTHARLKPVDLLYVNNSTISELPDAVFSNLSLHNLQLSS--CGIQRIATGAFK 125
            :|.|.::|:.|.|.         |.:.:..||.||..|.  |.:|:.|:.|  |.|:.:..    
 Frog    80 EQTDLTKLILASNK---------LQLLSEDISLLPALVV--LDIHDNQIVSLPCAIKELTN---- 129

  Fly   126 GQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQLSHIPD-------------------- 170
                 |:.||:..|.:..:|.| |:.|..|..|.|..|||..:||                    
 Frog   130 -----LQKLNISHNKIKQLPKE-LQHLQNLKSLLLQHNQLEELPDSIGHLSILEELDVSNNCLRS 188

  Fly   171 -DAFVG-LTKLSTLKLNDNNVTLASNAFRGLEQSLKNLNLKGTKQRKVPESIRGLKSLAFLDLSQ 233
             .:.|| ||.|....|:.|.:|...... |..::||.|:........||.|:.|::||..|.|.|
 Frog   189 ISSSVGQLTGLVKFNLSSNKLTALPTEI-GKMKNLKQLDCTSNLLENVPASVAGMESLEQLYLRQ 252

  Fly   234 NGIKELPGAGGIRVFDGLDALTALNLERNLIQSIGETAFAGVRKTLSSLSLLN---NLLAEFPIG 295
            |.:..||      ....|..|..|::..|.||::|....    :.|||||:|.   |.|...| .
 Frog   253 NKLTYLP------ELPFLTKLKELHVGNNQIQTLGPEHL----QNLSSLSVLELRYNKLKVLP-E 306

  Fly   296 AVHSLKELRVLDIGFNLLTSLPEAAFRGNPGITLLALDGNPLSSV 340
            .:..|..|..||:..|.|.||| ......|.:..|.|:||||..:
 Frog   307 EISLLNGLERLDLSNNDLGSLP-CTLGSLPNLKSLQLEGNPLRGI 350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hafNP_001356954.1 LRR <52..>252 CDD:227223 57/212 (27%)
leucine-rich repeat 86..105 CDD:275380 6/18 (33%)
leucine-rich repeat 106..129 CDD:275380 5/24 (21%)
LRR_8 131..189 CDD:338972 23/79 (29%)
leucine-rich repeat 131..154 CDD:275380 8/22 (36%)
leucine-rich repeat 155..178 CDD:275380 11/44 (25%)
leucine-rich repeat 179..202 CDD:275380 5/22 (23%)
leucine-rich repeat 203..225 CDD:275380 7/21 (33%)
leucine-rich repeat 226..253 CDD:275380 8/26 (31%)
LRR_8 254..337 CDD:338972 29/85 (34%)
leucine-rich repeat 254..302 CDD:275380 16/50 (32%)
leucine-rich repeat 303..326 CDD:275380 8/22 (36%)
leucine-rich repeat 327..350 CDD:275380 6/14 (43%)
PCC 332..>413 CDD:188093 5/9 (56%)
PRK10927 <1061..>1097 CDD:236797
lrrc40NP_001011310.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..26
LRR <82..348 CDD:227223 87/299 (29%)
LRR 1 83..104 7/29 (24%)
leucine-rich repeat 84..106 CDD:275380 7/30 (23%)
LRR 2 106..127 7/22 (32%)
leucine-rich repeat 107..129 CDD:275380 7/23 (30%)
LRR 3 129..151 7/31 (23%)
leucine-rich repeat 130..152 CDD:275380 8/22 (36%)
LRR 4 152..173 8/20 (40%)
leucine-rich repeat 153..175 CDD:275380 8/21 (38%)
LRR 5 175..196 2/20 (10%)
leucine-rich repeat 176..198 CDD:275380 3/21 (14%)
LRR 6 198..219 5/21 (24%)
leucine-rich repeat 199..221 CDD:275380 5/22 (23%)
LRR 7 221..242 6/20 (30%)
leucine-rich repeat 222..244 CDD:275380 7/21 (33%)
internalin_A 238..>583 CDD:380193 42/125 (34%)
LRR 8 244..265 8/26 (31%)
leucine-rich repeat 245..266 CDD:275380 8/26 (31%)
LRR 9 266..287 6/24 (25%)
leucine-rich repeat 267..290 CDD:275380 7/26 (27%)
LRR 10 290..311 7/21 (33%)
leucine-rich repeat 291..313 CDD:275380 7/22 (32%)
LRR 11 313..335 8/22 (36%)
leucine-rich repeat 314..336 CDD:275380 8/22 (36%)
LRR 12 336..357 6/15 (40%)
leucine-rich repeat 337..355 CDD:275380 6/14 (43%)
leucine-rich repeat 363..476 CDD:275380
LRR 13 429..450
LRR 14 453..475
LRR 15 476..497
leucine-rich repeat 477..522 CDD:275380
LRR 16 499..520
leucine-rich repeat 500..513 CDD:275380
LRR 17 522..543
leucine-rich repeat 523..546 CDD:275380
LRR 18 546..567
leucine-rich repeat 547..569 CDD:275380
LRR 19 569..590
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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