DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment haf and swi2

DIOPT Version :9

Sequence 1:	NP_001356954.1	Gene:	haf / 33339	FlyBaseID:	FBgn0261509	Length:	1347	Species:	Drosophila melanogaster
Sequence 2:	NP_611247.3	Gene:	swi2 / 37010	FlyBaseID:	FBgn0034262	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	64/304 - (21%)
Similarity:	103/304 - (33%)	Gaps:	81/304 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 QLSHIPDDAFVGLTKLSTLKLNDNNVTLASNAFRGLEQSLKNLNLKGTKQRKVPESIRGLKSLAF 228
            :||...||:....|.|:|:    ..:|                    |:...:|:|.|
  Fly    25 RLSRAADDSHETSTLLATI----TTIT--------------------TEIIPMPDSGR------- 58

  Fly   229 LDLSQNGIKELPGAGG-----------IRVFDGLDALTALNLERNL--IQSIGETAFAGVRK--- 277
               |..|....|.|.|           ::.:.|::.|.|||....|  :|...|....|..|
  Fly    59 ---SCFGWSSAPEAAGGNCSRSNRNGTLKCYGGMNNLAALNQSGKLSRVQPALEMLLCGWPKDGL 120

  Fly   278 ----TLSSLSLLNNLLAE----------FPIGAVHSLKELRVLDIGFNLLTSLPEAAFRGNPGIT 328
                .|..|..|.:|..|          ||     .:.||..::|.:..|:.:....|:....:.
  Fly   121 NHFRDLQKLPRLRSLTIEYSGFTEFKFDFP-----EMLELHTINISWTNLSYISSRTFKRVHPLK 180

  Fly   329 LLALDGNPLSSVPEGAFAHLNATLRGLSLGGRFLHCDCKLRWVAEWIRNGDLQVTSRERNPQFCG 393
            :|.|..|.|..: :|... |......|.|.|...:|....:|:......|.|.|   :|:...|
  Fly   181 VLDLRWNQLIQL-DGPLL-LPRNFEQLYLAGNPWNCTRNFKWLLLQPEKGRLVV---DRDELIC- 239

  Fly   394 TPPRFRDRGFYSIQPEEL----SCPDIADAALRGPVGLADNLKP 433
            |..::::|....:...:|    .|....|  ||....|..::.|
  Fly   240 TDRKYKERQMLMVMHYKLELKRQCQSHED--LRNCTCLMHHILP 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
haf	NP_001356954.1	LRR	<52..>252	CDD:227223	18/98 (18%)
		leucine-rich repeat	86..105	CDD:275380
		leucine-rich repeat	106..129	CDD:275380
		LRR_8	131..189	CDD:338972	7/24 (29%)
		leucine-rich repeat	131..154	CDD:275380
		leucine-rich repeat	155..178	CDD:275380	4/13 (31%)
		leucine-rich repeat	179..202	CDD:275380	3/22 (14%)
		leucine-rich repeat	203..225	CDD:275380	4/21 (19%)
		leucine-rich repeat	226..253	CDD:275380	6/37 (16%)
		LRR_8	254..337	CDD:338972	24/101 (24%)
		leucine-rich repeat	254..302	CDD:275380	16/66 (24%)
		leucine-rich repeat	303..326	CDD:275380	4/22 (18%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		PCC	332..>413	CDD:188093	18/84 (21%)
		PRK10927	<1061..>1097	CDD:236797
swi2	NP_611247.3	LRR	<117..384	CDD:227223	38/178 (21%)
		leucine-rich repeat	132..154	CDD:275378	5/26 (19%)
		leucine-rich repeat	155..178	CDD:275378	4/22 (18%)
		leucine-rich repeat	179..201	CDD:275378	6/23 (26%)
		leucine-rich repeat	202..214	CDD:275378	3/11 (27%)
		leucine-rich repeat	287..307	CDD:275378
		leucine-rich repeat	308..332	CDD:275378
		leucine-rich repeat	333..357	CDD:275378
		leucine-rich repeat	358..385	CDD:275378
		leucine-rich repeat	386..398	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24366
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100