DRSC/TRiP Functional Genomics Resources

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Protein Alignment haf and CG16974

DIOPT Version :9

Sequence 1:NP_001356954.1 Gene:haf / 33339 FlyBaseID:FBgn0261509 Length:1347 Species:Drosophila melanogaster
Sequence 2:NP_001246018.1 Gene:CG16974 / 34713 FlyBaseID:FBgn0032479 Length:1257 Species:Drosophila melanogaster


Alignment Length:453 Identity:117/453 - (25%)
Similarity:166/453 - (36%) Gaps:110/453 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 RLHVAHAQCPWQRD----VPDLQTSCICAYNLGRELSVQCDQVDFSQLLAAMNTHARLKPVDLLY 87
            :|.:||.  |..|.    :|.|::.        ||.|.|..::....|:.....    :|....|
  Fly   154 QLMLAHV--PADRSNPLKLPQLESL--------REFSWQSSELKDETLMELFTR----QPRSFEY 204

  Fly    88 VNNSTISE---------LPDAV------------FSNLSLHNL----QLSSCGIQR----IATGA 123
            :....::|         :|.||            .||.||.||    ||....:.|    .....
  Fly   205 MERLNLAENRLECLHWAIPLAVRRVKVLEMSGNRLSNCSLLNLQYMKQLQELHLDRSELTYLPQR 269

  Fly   124 FKGQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQLSHIPDDAFVGLTKLSTLKLNDNN 188
            |.|:.|.||.|||..|||.::|.:......||..|.||.|:||.:|...|.....|..|.|:||.
  Fly   270 FLGELSELRMLNLSQNLLTELPRDIFVGALKLERLYLSGNRLSVLPFMLFQTAADLQVLDLSDNR 334

  Fly   189 VTLASNAFRGLEQSLKNLNLKGTKQRKV-PESIRGLKSLAFLDLSQNGIKELPGAGGIRVFDGLD 252
            :....:.|......|:.|:|:..:.:.: ..|:..|:.|..||||||.:..:..    :.|:.||
  Fly   335 LLSFPDNFFARNGQLRQLHLQRNQLKSIGKHSLYSLRELRQLDLSQNSLSVIDR----KAFESLD 395

  Fly   253 ALTALNLERNLIQSIGETAFAGVRKTLSSLSLLNNLLAEFPIGAVHS------------------ 299
            .|.|||:..|.:..:....|..:. .|..|.|..|...:.|.|....                  
  Fly   396 HLLALNVSGNNLTLLSSIIFQSLH-ALRQLDLSRNQFKQLPSGLFQRQRSLVLLRIDETPIEQFS 459

  Fly   300 ---------------LKELRVLDIGFN-LLTSLPEAAFRGNPGITLLALDGNPLSSVP---EGAF 345
                           |..||.|.:..| .||.||...|...|.|..|.|..|.|..:|   .|..
  Fly   460 NWISRYDESLVDPQVLHRLRYLSVQQNRKLTYLPATLFANTPNIRELLLAENGLLQLPTQISGLS 524

  Fly   346 AHLNATLRGLSLGG--------RFLH----------CDCKLRWVAEWIRNGDLQVTSRERNPQ 390
            .....::||.|||.        |.||          |||.:.|:..|:.|  ...:.|.:.||
  Fly   525 RLQRLSVRGNSLGSLPENIKELRQLHYLNILGNEYQCDCSMYWLTAWLAN--TSTSLRHQMPQ 585

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hafNP_001356954.1 LRR <52..>252 CDD:227223 61/229 (27%)
leucine-rich repeat 86..105 CDD:275380 7/39 (18%)
leucine-rich repeat 106..129 CDD:275380 8/30 (27%)
LRR_8 131..189 CDD:338972 24/57 (42%)
leucine-rich repeat 131..154 CDD:275380 9/22 (41%)
leucine-rich repeat 155..178 CDD:275380 9/22 (41%)
leucine-rich repeat 179..202 CDD:275380 6/22 (27%)
leucine-rich repeat 203..225 CDD:275380 5/22 (23%)
leucine-rich repeat 226..253 CDD:275380 9/26 (35%)
LRR_8 254..337 CDD:338972 27/116 (23%)
leucine-rich repeat 254..302 CDD:275380 13/80 (16%)
leucine-rich repeat 303..326 CDD:275380 9/23 (39%)
leucine-rich repeat 327..350 CDD:275380 7/25 (28%)
PCC 332..>413 CDD:188093 22/80 (28%)
PRK10927 <1061..>1097 CDD:236797
CG16974NP_001246018.1 leucine-rich repeat 206..228 CDD:275380 4/21 (19%)
leucine-rich repeat 229..252 CDD:275380 6/22 (27%)
LRR_RI <246..433 CDD:238064 58/191 (30%)
LRR_8 251..311 CDD:290566 21/59 (36%)
leucine-rich repeat 253..276 CDD:275380 4/22 (18%)
leucine-rich repeat 277..300 CDD:275380 9/22 (41%)
leucine-rich repeat 301..324 CDD:275380 9/22 (41%)
LRR_8 325..383 CDD:290566 18/57 (32%)
leucine-rich repeat 325..348 CDD:275380 6/22 (27%)
leucine-rich repeat 349..372 CDD:275380 5/22 (23%)
LRR_RI 351..>557 CDD:238064 52/210 (25%)
LRR_8 371..431 CDD:290566 20/64 (31%)
leucine-rich repeat 373..396 CDD:275380 9/26 (35%)
leucine-rich repeat 397..420 CDD:275380 6/23 (26%)
leucine-rich repeat 421..444 CDD:275380 6/22 (27%)
LRR_8 477..536 CDD:290566 19/58 (33%)
leucine-rich repeat 478..502 CDD:275380 9/23 (39%)
leucine-rich repeat 503..526 CDD:275380 7/22 (32%)
Ig <714..761 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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