DRSC/TRiP Functional Genomics Resources

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Protein Alignment haf and AgaP_AGAP012425

DIOPT Version :9

Sequence 1:NP_001356954.1 Gene:haf / 33339 FlyBaseID:FBgn0261509 Length:1347 Species:Drosophila melanogaster
Sequence 2:XP_320129.3 Gene:AgaP_AGAP012425 / 1280456 VectorBaseID:AGAP012425 Length:472 Species:Anopheles gambiae


Alignment Length:481 Identity:111/481 - (23%)
Similarity:187/481 - (38%) Gaps:109/481 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 SCICAYNLGRELSVQCDQVDFSQLL------AAMNTHARLKPVDLLYVNNSTISELPDAVFSNLS 105
            ||.|..:.|   ...|........|      .::||:.  ....|:::.::.:.|:..  |.:::
Mosquito    19 SCNCIKDKG---VFDCTSKQIGATLFPLEDWQSLNTNG--LDAKLVFLVSTGLKEITH--FPSMN 76

  Fly   106 LHNLQLSSCGIQRIATGAFKGQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQL----- 165
            :..|.||...|..:.||.|       .||.|                  |.:||||.|:|     
Mosquito    77 VTWLDLSHNEIATMKTGCF-------ANLTL------------------LQVLDLSHNRLKSESL 116

  Fly   166 ------SHIPDDAFVGLTKLSTLKLNDNNV-TLASNAFRGLEQSLKNLNLKGTKQRKVPE----S 219
                  .|...:.::.|:||..|:|..|:: :|..:.|..| .:|:.|:|:....:.:.:    :
Mosquito   117 NPDVFAGHYSTNEYMPLSKLRVLRLGANDLHSLNPDLFEHL-PALEELSLELNPFKVIDQQSEIA 180

  Fly   220 IRGLKSLAFLDLSQNGIKELPGAGGIRVFDGLDALTALNLERNLIQSIGETAFAGVRKTLSSLSL 284
            |..::.|..||||...::::|.    .:|.....|..|||..||:|.:  .|.......|:.|||
Mosquito   181 IASIERLVSLDLSYMELEDIPK----YLFHTPRGLRYLNLTGNLLQEV--PAALSYATALAWLSL 239

  Fly   285 LNNLLAEFPIGA-VHSLKELRVLDI------------GFNLLTSLPEAAFRGNPGITLL------ 330
            ..|.::...:|. ..|||:|..|.:            .|:.|.||.|.....||.:|.|      
Mosquito   240 DENPISSIVVGTEFPSLKQLTFLSLSYMSQLKVIGRGAFSGLESLQEVHITNNPHLTYLHGHAFV 304

  Fly   331 --------ALDGNPLSS--VPEGAFAHLNA-------TLRGLSLGGRFLHCDCKLRWVAEWIRNG 378
                    .||..|:..  :.....::|:|       |:..:.:......|||..|||...:...
Mosquito   305 RNDTDNPERLDWPPVKRLYLHNNNISYLDAQLLVQWDTMDVIDIRANPWTCDCTNRWVLLSLLPI 369

  Fly   379 DLQVTSRERNPQFCGTPPRFRDRGFYSIQPEE--LSCPDIA------DAALRGPVGLADNLKPTL 435
            ..:.|....|...|.:|.:........::.::  |.|||.|      |.||.  :||...:...:
Mosquito   370 IERTTPAILNNIDCKSPSQMAGLSMVDLEHKQTHLRCPDEAGNNPSNDGALL--MGLLIGVLLAI 432

  Fly   436 P-SSPDSVEYETGTGTGTVGTGTAAS 460
            | ::.....|:.|. .|..|:||.|:
Mosquito   433 PLTAAIWCVYKRGC-FGLFGSGTPAA 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hafNP_001356954.1 LRR <52..>252 CDD:227223 46/221 (21%)
leucine-rich repeat 86..105 CDD:275380 2/18 (11%)
leucine-rich repeat 106..129 CDD:275380 7/22 (32%)
LRR_8 131..189 CDD:338972 17/68 (25%)
leucine-rich repeat 131..154 CDD:275380 3/22 (14%)
leucine-rich repeat 155..178 CDD:275380 9/33 (27%)
leucine-rich repeat 179..202 CDD:275380 7/23 (30%)
leucine-rich repeat 203..225 CDD:275380 4/25 (16%)
leucine-rich repeat 226..253 CDD:275380 7/26 (27%)
LRR_8 254..337 CDD:338972 30/109 (28%)
leucine-rich repeat 254..302 CDD:275380 16/48 (33%)
leucine-rich repeat 303..326 CDD:275380 8/34 (24%)
leucine-rich repeat 327..350 CDD:275380 6/38 (16%)
PCC 332..>413 CDD:188093 17/91 (19%)
PRK10927 <1061..>1097 CDD:236797
AgaP_AGAP012425XP_320129.3 LRR_RI <55..267 CDD:238064 60/245 (24%)
LRR_8 76..146 CDD:290566 24/94 (26%)
leucine-rich repeat 77..100 CDD:275380 9/29 (31%)
leucine-rich repeat 101..135 CDD:275380 9/33 (27%)
LRR_8 134..194 CDD:290566 16/60 (27%)
leucine-rich repeat 136..159 CDD:275380 7/23 (30%)
leucine-rich repeat 160..186 CDD:275380 4/25 (16%)
LRR_8 186..244 CDD:290566 20/63 (32%)
leucine-rich repeat 187..210 CDD:275380 7/26 (27%)
leucine-rich repeat 211..233 CDD:275380 8/23 (35%)
leucine-rich repeat 234..258 CDD:275380 8/23 (35%)
LRR_8 257..329 CDD:290566 15/71 (21%)
leucine-rich repeat 259..283 CDD:275380 4/23 (17%)
leucine-rich repeat 284..305 CDD:275380 6/20 (30%)
leucine-rich repeat 343..355 CDD:275378 0/11 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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