| Sequence 1: | NP_001356954.1 | Gene: | haf / 33339 | FlyBaseID: | FBgn0261509 | Length: | 1347 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_612449.2 | Gene: | VASN / 114990 | HGNCID: | 18517 | Length: | 673 | Species: | Homo sapiens |
| Alignment Length: | 805 | Identity: | 191/805 - (23%) |
|---|---|---|---|
| Similarity: | 275/805 - (34%) | Gaps: | 245/805 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 16 PLLLLL---PLILGRLHVAHAQCPWQRDVPDLQTSCICAYNLGRELSVQCDQVDFSQLLAAMNTH 77
Fly 78 ARLKPVDLLYVNNSTISELPDAVFSNLSLHNLQLSSCGIQRIATGAFKGQESVLRNLNLQDNLLA 142
Fly 143 DVPVEALKVLGKLNLLDLSKNQLSHIPDDAFVGLTKLSTLKLNDNNVT-LASNAFRGLEQSLKNL 206
Fly 207 NLKGTKQRKVPESIRGLKSLAFLDLSQNGIKEL-PGAGGIRVFDGLDALTALNLERNLIQSIGET 270
Fly 271 AFAGVRKTLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGFNLLTSLPEAAFRGNPGITLLALDGN 335
Fly 336 -------------------------PLSSVPEGAFAHLNATLRGLSLGGRFLHCDCKLRWVAEWI 375
Fly 376 RNGDLQVTSRERNPQFCGTPPRFRDRGFYSIQPEELSCPDIADAALRGPVGLADNLKPTLPSSPD 440
Fly 441 SVEYETGTGTGTVGTGTAASAPVTSSVSSSTSTTTPTTTTTTTTAEPTTRRSTTRPPTKSTTTIS 505
Fly 506 ATTASPASNPP---VNGTGTVQATSITTSSSSSSSSSTSTGHGNGKQAPGWRQGVTNGNGNSGVG 567
Fly 568 GAGGLHKP----QRPP--LVLGYPPQRGTRIDDANEVQVKHAFRQDSSVIIQWDSDTANILGFRV 626
Fly 627 VYRLFGEKAFKQGPP-------LESSEREFKIKNVPAQECIIVCVISLEELHVTPETVP--YQQC 682
Fly 683 REVRTVASQASNMDKITIAAS-------AAICGTIIVAVIVFIAAS---RRSRKLQSSQQ----- 732
Fly 733 ---KSPLPIGGLPVNCCGPTGSPGP 754 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| haf | NP_001356954.1 | LRR | <52..>252 | CDD:227223 | 56/201 (28%) |
| leucine-rich repeat | 86..105 | CDD:275380 | 3/18 (17%) | ||
| leucine-rich repeat | 106..129 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 131..189 | CDD:338972 | 21/57 (37%) | ||
| leucine-rich repeat | 131..154 | CDD:275380 | 7/22 (32%) | ||
| leucine-rich repeat | 155..178 | CDD:275380 | 10/22 (45%) | ||
| leucine-rich repeat | 179..202 | CDD:275380 | 7/23 (30%) | ||
| leucine-rich repeat | 203..225 | CDD:275380 | 7/21 (33%) | ||
| leucine-rich repeat | 226..253 | CDD:275380 | 9/27 (33%) | ||
| LRR_8 | 254..337 | CDD:338972 | 21/107 (20%) | ||
| leucine-rich repeat | 254..302 | CDD:275380 | 7/47 (15%) | ||
| leucine-rich repeat | 303..326 | CDD:275380 | 8/22 (36%) | ||
| leucine-rich repeat | 327..350 | CDD:275380 | 9/47 (19%) | ||
| PCC | 332..>413 | CDD:188093 | 22/105 (21%) | ||
| PRK10927 | <1061..>1097 | CDD:236797 | |||
| VASN | NP_612449.2 | LRR 8 | 217..238 | 7/21 (33%) | |
| leucine-rich repeat | 218..240 | CDD:275380 | 8/22 (36%) | ||
| LRR 9 | 240..262 | 6/21 (29%) | |||
| leucine-rich repeat | 241..265 | CDD:275380 | 5/23 (22%) | ||
| LRR 10 | 265..287 | 3/22 (14%) | |||
| leucine-rich repeat | 266..286 | CDD:275380 | 3/20 (15%) | ||
| LRRCT | 298..349 | CDD:214507 | 12/52 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 358..404 | 14/55 (25%) | |||
| EGF | 409..440 | CDD:278437 | 11/49 (22%) | ||
| fn3 | 466..535 | CDD:278470 | 18/88 (20%) | ||
| LRRNT | 23..54 | CDD:214470 | 12/72 (17%) | ||
| leucine-rich repeat | 34..56 | CDD:275380 | 7/41 (17%) | ||
| LRR 1 | 52..74 | 8/28 (29%) | |||
| leucine-rich repeat | 57..77 | CDD:275380 | 6/19 (32%) | ||
| LRR_8 | 62..112 | CDD:290566 | 17/50 (34%) | ||
| LRR_4 | 76..117 | CDD:289563 | 14/41 (34%) | ||
| LRR 2 | 77..98 | 6/21 (29%) | |||
| leucine-rich repeat | 78..101 | CDD:275380 | 7/22 (32%) | ||
| LRR_8 | 101..158 | CDD:290566 | 20/57 (35%) | ||
| LRR_4 | 101..141 | CDD:289563 | 14/39 (36%) | ||
| LRR 3 | 101..122 | 8/20 (40%) | |||
| leucine-rich repeat | 102..125 | CDD:275380 | 10/22 (45%) | ||
| LRR_8 | 124..228 | CDD:290566 | 34/137 (25%) | ||
| LRR 4 | 125..146 | 6/20 (30%) | |||
| leucine-rich repeat | 126..149 | CDD:275380 | 7/22 (32%) | ||
| LRR 5 | 149..170 | 7/23 (30%) | |||
| leucine-rich repeat | 150..193 | CDD:275380 | 17/56 (30%) | ||
| LRR 6 | 171..191 | 10/30 (33%) | |||
| LRR 7 | 193..214 | 5/40 (13%) | |||
| leucine-rich repeat | 194..217 | CDD:275380 | 5/42 (12%) | ||
| LRR_8 | 216..273 | CDD:290566 | 14/57 (25%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||