DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31935 and AT5G55060

DIOPT Version :9

Sequence 1:	NP_608608.2	Gene:	CG31935 / 33338	FlyBaseID:	FBgn0051935	Length:	916	Species:	Drosophila melanogaster
Sequence 2:	NP_200317.2	Gene:	AT5G55060 / 835597	AraportID:	AT5G55060	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	147/552 - (26%)
Similarity:	240/552 - (43%)	Gaps:	115/552 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 VPAKAPLGKIYLSVEASSYLSCCLRDYQSVAEVTRSLESFVGRNFSGTSS---GAEAASNPLDRI 377
            :|..:.:.::.:::||..... .::|:.:.:..:..:....|.:.|...|   |.:......|..
plant   134 IPLASVVKQLAVAIEAGKRAK-NVKDFVASSGSSSPVRERGGLSLSAVKSLVLGEKEDKLGFDSG 197

  Fly   378 TEHKLTKRRERSFELPSQAGLTKR-----LPGPMTESELSELLAYLFPDMHPEMALFPYAKKNFT 437
            .|.||.......|.:.|  |...|     |..|...|..::       |:|
plant   198 DEDKLVSLINALFNVDS--GFLSRKIVSDLESPTNRSSFAK-------DLH-------------- 239

  Fly   438 DKFDPMRIKSAVPDSLVCRLSCLLATCHAHLGSVEGMAQVWAAFTRQLRLLWDNSLMVPGISA-G 501
                     :|.|.|.|.:|:.::.:    ..:...||..|.....:||..|:....:|.|.. .
plant   240 ---------AAPPSSFVVKLAEVIGS----FTTPRRMALFWCRVVEELRRFWNEEKHIPWIPLDN 291

  Fly   502 FPDTRTCLLHQKLQMLNVCVERRVQREANSKRKSEGMVGKASSEEEEDEDDDEGEFFDCDDLTAG 566
            .||.::|||||.||::|.|:.|:.:..|.|:.....|...:|:.|:.|..:..|      .|...
plant   292 NPDLKSCLLHQWLQVINCCLARKARNVAASEALDAVMRQASSANEKSDVSESMG------SLLYA 350

  Fly   567 AGSPTKAVLSLKPEGRLRRLNNERLLE--EPDEYLYIPDTQEPVPKTEDQLQDDAEVMLKLGP-G 628
            ..:..:.:|.|   |...::.|..:||  ||   :|.|.|||....|||.:::..|::|:.|. |
plant   351 KSNSGELILRL---GVYNQVENLTMLETGEP---VYSPITQEGPLLTEDLIRETEELVLRTGSMG 409

  Fly   629 SGLTTQMMCTSLLSDMEAFKAANPRGIMEDFIRWYSPKDWEE----VTDELGQVKHQLSIRMTTE 689
            :|      |:.|||||:|||||||..|:|||:||:||.||.|    ..|:...|:.|||.||..|
plant   410 AG------CSQLLSDMQAFKAANPGCILEDFVRWHSPPDWTENGNMSGDDSSPVRGQLSTRMQKE 468

  Fly   690 GNTWQKVWEQAQAVPVSRQKRLFDDTNEALKVLHYLETRKMHEIYNLTVIPLLHSAILKLADIL- 753
            ||.|:::||.|:.:|..:|..|||:......:|:|||.....|::......|:....:.:..:|
plant   469 GNLWRELWETAKPLPAVKQAPLFDEDLAVEGILNYLEDIPAAELFEQLFTSLVSLGFVMVEPVLA 533

  Fly   754 SNAELEDLF-------------SSQIEKLLSDLCRL----------------SRSHSDELPSIKP 789
            :|.:|..||             .:..:| |.|||::                |...::|.||
plant   534 TNDDLSKLFFECKDYVVAICQGGAWTDK-LDDLCQVYETVETMLLRPEEVLRSMKQTEESPS--- 594

  Fly   790 LLDDLAELERRFYQFKCFERLSGYPKRSSLQQ 821
               ..:|.:||      |:|| |:..|.|.::
plant   595 ---SGSETKRR------FKRL-GFIFRGSKER 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31935	NP_608608.2	Rab3-GTPase_cat	578..726	CDD:290601	64/154 (42%)
AT5G55060	NP_200317.2	Rab3-GTPase_cat	356..505	CDD:290601	66/160 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	113	1.000	Domainoid score	I2051
eggNOG	1	0.900	-	-		E1_KOG2390
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D536022at2759
OrthoFinder	1	1.000	-	-		FOG0005064
OrthoInspector	1	1.000	-	-		otm3332
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21422
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3584
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.920