Protein Alignment Rab3GAP1 and rab3gap1

DIOPT Version :10

• Sequence 1: NP_608608.2
• Gene: Rab3GAP1 / 33338
• FlyBaseID: FBgn0051935
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: XP_073768360.1
• Gene: rab3gap1 / 777744
• ZFINID: ZDB-GENE-061027-53
• Length: 983
• Species: Danio rerio
• Alignment Length: 1031
• Identity: 293/1031 - (28%)
• Similarity: 461/1031 - (44%)
• Gaps: 165/1031 - (16%)

  Fly     1 MAEEID-DNEFYR-ENFSADSDWEVFNAQLGEILQKWDVSSDSETRNLKSEEIFSCNWKVEREKL 63
            ||.:.| ::|.:. .:|:..|:||.|.:::.|:|..|.:......:.|:..|..|..|:...:::
Zfish     1 MAADSDPESEVFEITDFTTASEWERFISRVEEVLNDWKLIGSRVGKPLEKGEYTSGTWEESSQEI 65

  Fly    64 DMLRNGIEVEYHQAILEDEELVRAEAKEITCLQRTSCHHDLMSTGNSFGPPIRSSQELHILARIY 128
            ........:.:|  .|:.|........|:..........||:...|.|.|      ..|.|.|.:
Zfish    66 SFADFKFSITHH--YLKQESAENDGRDELEEDAYPLAMQDLLCINNDFPP------RAHCLVRWF 122

  Fly   129 GLRRFIVLHPVNPTLNYMRSTSEFNFFLSAVAVVSAEVQSLVPIFVQIYDPKWNYYTGVALAPAL 193
            |:|.|:|:.| ......:.|.|:.:..||:|::..|.....||:||||.......::|....|.:
Zfish   123 GVREFVVISP-GANCEAIISESKCSLLLSSVSIALANTGCQVPLFVQIQQKHRKMFSGECQGPGV 186

  Fly   194 RTNFRLIGLEKAPPECRFLMGLLTLFREKV--PTSYTQAAMISVCTTYAL-DTMRIRMPMYVPFD 255
            |::|.::.|.:.|.:...|.|||.:|:.|:  |.:......||:..||.| |..:...|...|
Zfish   187 RSDFEMVHLRRVPSQYNHLSGLLDIFKNKIGCPLTPLPPINISIRFTYVLQDWQQCSWPQQPP-- 249

  Fly   256 HGLSSEDIVVDGEVSHLEVQQFCALPHGYKPESRTEIYLVYTWPELSEHVAFDSEQRSDFVPAKA 320
                ..|.::.|||..:|   |..||.|...:..:|::|..|||.|:|.:..|::..||..|.:|
Zfish   250 ----DFDALLAGEVGGVE---FGKLPFGACEDPISELHLAATWPSLTEGIVVDNDVYSDLDPLQA 307

  Fly   321 P---------------LGKIYLSVEASSYLSCCLRDYQSVAEVTRSLESFVGRNFSGTSSGAEAA 370
            |               ||:.     .:.:...|.|...:...:.||.....|:..|..:......
Zfish   308 PHWSVRVRTAENPQCLLGEF-----LTEFFKICCRKETTEEILGRSTAEEEGKENSDITQALSKL 367

  Fly   371 SNPLDRITEHKLT---------KRRERSFELPSQAGLTKRLPGPMTESELSELLAYLFPD----- 421
            :.|...:..|||:         ||..|...:|.         .|:....|:.:|.|||||
Zfish   368 TEPSTAVPIHKLSVSSMVHSARKRIRRHRRVPE---------SPLNNDVLNSILLYLFPDAALDK 423

  Fly   422 ----------MHPEMALFPYAKKNFTDKFDPMRIKSAVPDSLVCRLSCLLATCHAHLGSVEGMAQ 476
                      ..|:.....|...|        ::||...|||..||:..:...:.|.|.|..:|.
Zfish   424 ADVSEVRPPQQSPDRQSEDYHLYN--------QLKSCPSDSLTHRLALCICMVNFHHGGVRAVAH 480

  Fly   477 VWAAFTRQLRLLWDNSLMVPGISAGFPDTRTCLLHQKLQMLNVCVERRVQREANSKRKS------ 535
            :|..|..::|..|:|:.::.|:::|.||.|.|||||||||||.|:||:..|:...|..|
Zfish   481 LWQEFVLEMRYRWENNCLIYGLASGPPDLRCCLLHQKLQMLNCCIERKKARDDGKKSSSSDGARD 545

  Fly   536 -----------EGM-VGKASSEEEEDEDDDEGEFFDC----DDLTAGAGSPTKAVLSLKPEGRLR 584
                       ||. ..:|:.:..:...|.|.|||:|    :::............| ||||||:
Zfish   546 RSRGAPEGAGPEGAGPAEAAGKSWDSWSDSEDEFFECVSDTEEMKEDKEEAENRSRS-KPEGRLQ 609

  Fly   585 RLNNERLL--EEPDEYLYIPDTQEPVPKTEDQLQDDAEVMLKLG---PGSGLTTQMMCTSLLSDM 644
            ......||  :||   ||||.||||.|.|||.|::.:||:.|||   .|:.|..:|....|||||
Zfish   610 PHGTHTLLNTQEP---LYIPITQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDM 671

  Fly   645 EAFKAANPRGIMEDFIRWYSPKDW--EEVTDELG--QVKHQLSIRMTTEGNTWQKVWEQAQAVPV 705
            |:||||||...:.||:|||||:|:  |:|||..|  :|:.:||.||...||.|.:.||.|:|.|.
Zfish   672 ESFKAANPGCTLLDFVRWYSPRDYVEEQVTDADGRVEVRGELSARMKIPGNMWVEAWETARATPA 736

  Fly   706 SRQKRLFDDTNEALKVLHYLETRKMHEIYNLTVIPLLHSAILKLADILSNAELEDLFSSQIEKLL 770
            .|||||||||.||.||||||..:|..|:....:..:||:|:||:.:..|..:|..:.|| ::::.
Zfish   737 RRQKRLFDDTKEAEKVLHYLALQKPSELTRHLLPCVLHAALLKIKEEESAEDLPSVRSS-LQQIS 800

  Fly   771 SDLCRLSRSHSDELPSIKPLLDDLAELERRFYQFKCFERLSGY-----PKRSSLQQVKLQFEEIL 830
            |...::.|..:.|...::.::..|..:|....:.:..:...|.     .:.....:::.....:|
Zfish   801 SSASKILRHPNPEFKKLEDVISQLMAVEAVIARARSLKAKFGVCGGEREREEDGDELERFVSSLL 865

  Fly   831 RNDNCCT----------------IVNRRLTAAGD-GTLYDI----LIPKLEEDMA-----DRLIS 869
            .....|.                :.::||..:.| |.|.|:    |.|..||.:.     ||...
Zfish   866 EEPEVCVSGAGRGPAGNVIHKLFVSSQRLADSSDEGFLVDVEAALLAPMEEETLRSGGSDDRKAF 930

  Fly   870 KDY--------IIRLDGDTKTTEKGLYLG--PQFMRAIVTGEKLRLCGAFTESTAF 915
            .|:        ::|    |.......|..  ||.:..::..::.||.|||:..|:|
Zfish   931 PDFPPPAGREILLR----TCVPRPAPYSKALPQRLFCVLMRDEFRLAGAFSSDTSF 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3GAP1	NP_608608.2	Rab3-GTPase_cat	578..726	CDD:464022	85/156 (54%)
rab3gap1	XP_073768360.1	None