Protein Alignment CG31935 and rbg-1

DIOPT Version :9

• Sequence 1: NP_608608.2
• Gene: CG31935 / 33338
• FlyBaseID: FBgn0051935
• Length: 916
• Species: Drosophila melanogaster
• Sequence 2: NP_510490.1
• Gene: rbg-1 / 181595
• WormBaseID: WBGene00004317
• Length: 915
• Species: Caenorhabditis elegans
• Alignment Length: 1044
• Identity: 228/1044 - (21%)
• Similarity: 373/1044 - (35%)
• Gaps: 305/1044 - (29%)

  Fly     4 EIDDNEFYREN-FSADSDWEVFNAQLGEILQKWDVSSDSETRNLKSEEIFSCNWKVEREKLDMLR 67
            ||::|..:..| |:..:|.|.|.|....||||::.||   .|...|.::.......:...:.:..
 Worm     3 EIEENTVFEINDFTIVTDMEHFGAAFEGILQKYEFSS---RRPCLSNDVKYRLIVTDTNMISIGE 64

  Fly    68 NGIEVEYHQAI------LEDEELVRAEAKEITCLQRTSCHHDLMSTGNSFGPPIRSSQELHIL-- 124
            |.:.:|..|.:      ..|.|.|.|...||                         .::.|::
 Worm    65 NKLRIELLQPVPASSNPSNDVEFVEAPKDEI-------------------------EEDAHVIPF 104

  Fly   125 ------ARI-------------YGLRRFIVLHPVNPTLNYMRSTSEFNFFLSAVAVVSAEVQSLV 170
                  |.:             :|:|..|::.| |.:.......::.|..:..:..:....:..|
 Worm   105 TVAEEVANLKHGFEVTDSFLLKFGIRECIIISP-NDSSGTFTDENQVNTVMGNIKTILHSSRCEV 168

  Fly   171 PIFVQIYDPKWNYYTGVALAPALRTNFRLIGLEKAPPECRFLMGLLTLFREKVPTSYTQAAMISV 235
            |:|..|.|...:..:|.|.......||..:.|.........:..||.||:|.:..        |:
 Worm   169 PVFCYIKDQSLDMISGYASDGNSTYNFSSVVLRNINRRHCSMTDLLYLFKEHLGA--------SI 225

  Fly   236 CTTYALDTMRIRMPMYVPF-------DHGLSSEDIVVDGEVSHLEVQQFCALPHGYKPESRTEIY 293
            ...:....|..|....||.       :|.:.:..::..|..|.|             |....||
 Worm   226 SAFHEEVRMSSRFTHVVPLKQSKYFRNHTVETFGLLATGPTSSL-------------PFDILEI- 276

  Fly   294 LVYTWPELSEHVAFDSEQRSDFVPAKAPLGKIYLSVEASSYLSCCLRDYQS------------VA 346
             ..||....|:...::...|||            .:..|||.:..::..:|            ..
 Worm   277 -AATWRFFRENSLTENHSHSDF------------DINYSSYWNIKMKSTKSSLLGVLDEILGVYR 328

  Fly   347 EVTR-SLES------FVGRNFSGTSSGAEAASNPLDRIT-----EHKLTKRRERSFELPSQAGLT 399
            |.|| ::.|      .:|::::     .:...|...::|     |.|:.|..|     ...:|..
 Worm   329 EDTRKAIRSDLNCALILGKHYT-----QKELPNAFQKLTINSASEVKIGKHAE-----TEDSGTN 383

  Fly   400 KRLP-------------------------------GPMTESELSE-------LLAYLFPDMHPEM 426
            ..:|                               ..|:|::||:       .|..||...:|:.
 Worm   384 GPMPPALMKSWVNFIFNEAESDNESLAHELNMLNAASMSENQLSDDELVNNVKLDTLFNYKNPKS 448

  Fly   427 A---LFPYAKKNFTDKFDPMRIKSAVPDSLVCRLSCLLATCHAHLG-SVEGMAQVWAAFTRQLRL 487
            |   |.||              |.|...::..||:..||.....:. ......|:|..|..:||.
 Worm   449 ANTFLAPY--------------KCAKKSTVTWRLAIALANARVFMSDQPRAEPQLWVEFLLKLRE 499

  Fly   488 LWDNSLMVPGISAGFPDTRTCLLHQKLQMLNVCVERRVQREANSKRKSEGMVGKASSEEEEDEDD 552
            .::....|..:..|. |...|...||:|||.:|::.|        :|...|:..|.|....||..
 Worm   500 KYEKMETVEKVYNGI-DHLQCSFSQKMQMLQLCIDAR--------QKRHRMLDSAHSANNSDEFF 555

  Fly   553 DEGEFFDCDDLTAGAGSPTKAVLSLKPEGRLRRLNNERLLEEPDEYLYIPDTQEPVPKTEDQLQD 617
            |..|.|:.:           .:|....|||| :|....|:|.||..:|||.||:..|.|::.:..
 Worm   556 DANESFNAE-----------TILEPNNEGRL-KLFGLNLVEIPDVPMYIPVTQDACPLTDEMIDA 608

  Fly   618 DAEVMLKLGPGSGLTTQMMCTSLLSDMEAFKAANPRGIMEDFIRWYSPKDWEEVTDELGQVKHQL 682
            ..|.:..|.....:..||....  |||::|||||...:..||:||:||||::|.|:.:.:
 Worm   609 RNEHLFSLDEEDRVHLQMELVK--SDMQSFKAANAGAVFADFLRWHSPKDYDEKTNTISE----- 666

  Fly   683 SIRMTTEGNTWQKVWEQAQAVPVSRQKRLFDDTNEALKVLHYLETRKMHEIYNLTVI-------- 739
              ||....|.|.:.||.|..:||:.|.|:|:||..|.::|         ||:|...:
 Worm   667 --RMLISNNVWVRSWEAALPIPVANQARIFNDTKIAEEIL---------EIFNNATLDQVREWMK 720

  Fly   740 PLLHSAIL---------------------KLADILSNAELED--LFSSQIEKLLSDLCRLSRSHS 781
            |.:.:|.|                     |.|.||:||.|.:  :..::|.|..|.:
 Worm   721 PTVFAATLERLTEIESSYGVSEEKQKQRTKTAKILANATLNNTPMDYNEISKYCSQI-------- 777

  Fly   782 DELPSIKPLLDDLAELERRFYQFKCFERL-SGYPKRSSLQQVKLQFEEI-LRN--DNCC----TI 838
            :.:.::|..|..|.|..|        |:: ..||..:.:|....|...| :.|  ||..    |.
 Worm   778 EMIHNMKVHLMQLFENAR--------EKMHPPYPSETDVQSAIKQLVNIAVHNLWDNSTDEEPTF 834

  Fly   839 VNRRLTAAGDGTLYDILIPKLEEDMADRLIS---KDYII----------------RLDGDTKTTE 884
            |.:.....|...   .:|.||:|....:||:   |:||.                |:..|.::.:
 Worm   835 VIKPQDPIGRAI---AVIGKLDELTEQQLINGHRKEYIFNWKHSCPSTTTIPMTHRMYADLRSDK 896

  Fly   885 KGLY 888
            ..||
 Worm   897 HSLY 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31935	NP_608608.2	Rab3-GTPase_cat	578..726	CDD:290601	54/147 (37%)
rbg-1	NP_510490.1	Rab3-GTPase_cat	572..704	CDD:290601	53/141 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159179
Domainoid	1	1.000	96	1.000	Domainoid score	I4631
eggNOG	1	0.900	-	-		E1_KOG2390
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H45617
Inparanoid	1	1.050	160	1.000	Inparanoid score	I2881
Isobase	1	0.950	-	0	Normalized mean entropy	S6808
OMA	1	1.010	-	-		QHG59936
OrthoDB	1	1.010	-	-		D105289at33208
OrthoFinder	1	1.000	-	-		FOG0005064
OrthoInspector	1	1.000	-	-		oto20682
orthoMCL	1	0.900	-	-		OOG6_103581
Panther	1	1.100	-	-	LDO	PTHR21422
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2744
SonicParanoid	1	1.000	-	-		X3584
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.880