Protein Alignment nis and C10h16orf96

DIOPT Version :10

• Sequence 1: NP_608605.1
• Gene: nis / 33337
• FlyBaseID: FBgn0031347
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_063126146.1
• Gene: C10h16orf96 / 100361104
• RGDID: 2320756
• Length: 1725
• Species: Rattus norvegicus
• Alignment Length: 639
• Identity: 134/639 - (20%)
• Similarity: 221/639 - (34%)
• Gaps: 173/639 - (27%)

  Fly    36 RLEVLDEVVEQEDYMVANVR--LQSSLLTLGNTSKFRLFAGADAEEGAAAEPAAEPPAEEAEAPP 98
            ||..|:|..::.:|.:...|  ::...:.....|::|                  .|.||.....
  Rat  1007 RLPGLEERGDEYEYFLPGPREEMRMDEIPQEEISEYR------------------APQEEISEYG 1053

  Fly    99 APVEEPPAADPAPEP-APEPAP-----------EPAAEEPAPAEPVPEEAAPAEAAAPSPEPVGS 151
            ||.||.|:...:.|. :.|.||           |..::..||....|:|......|   |:.|||
  Rat  1054 APEEEIPSEGASQEEMSTEGAPSDGIRKGRVPREKISKVKAPRYRTPKERVSHHRA---PKDVGS 1115

  Fly   152 NHEPTPSATP------------------APEEHPPSEPEA------------------------- 173
            ........||                  |.|:...:.|.|
  Rat  1116 QEMVIKEETPEVKVLKKVIYKDKTQKDKASEQRHKAPPPALKKLRSAITIAAAAAAAYAAAANSA 1180

  Fly   174 -----DTSKAPMDVPAEAKGEELAPQASRVSSRSSGRDKSHSQTDGSLTNNLLRLERRLSKIELQ 233
                 |.:||..||||    .::|.:||||:|         |...|:..:.|....||.:.|.|.
  Rat  1181 AQVAKDAAKAIQDVPA----TQMAAEASRVAS---------SVPLGAFADILGAGFRRGATINLP 1232

  Fly   234 KEQATMEVQQFVSNLTSQLK-------ITMEQVNNMTHLLIDRKPNPQRFRLLRHIAKQLRVLMV 291
            .....||  :|....|:...       ::...:|.|.....:.|....::. :.|||:.
  Rat  1233 FRDEEME--EFPEEFTAPFNPFPAKPVLSQAMINAMYATSPEEKKKAVQYS-MSHIAQM------ 1288

  Fly   292 TTGDEVSVSWSSGDIVDGVEEEGLSEEEVPVESSAPTEVEKPEEEEELELEQPLCYSPEKMLTEL 356
                             .:..:.|.||...:.::               |.|.|.|        |
  Rat  1289 -----------------PIRHDSLKEEFANLSTN---------------LNQRLNY--------L 1313

  Fly   357 LDLKSQFCALTNKVNELAAALLKQDSQRLMDQMKD--LSETVRDIKLYMASNKEATNGMMTRLND 419
            .::.|. ..|.|.||.|...::.....||.::..:  ....:..:|.:......|...:..|::|
  Rat  1314 ANMGSS-GVLGNTVNVLEEKIVNLQKARLQEEELERVWGHQIDTMKSHYMVLDRAVERLQVRMDD 1377

  Fly   420 CVYQIQVLKKSASHLDEVKIDKTEVELLLAEKVDFQQLATKVSLEQLEEYKARLEQMFCEVRHIV 484
                ::|||.....||.||.|||.::|.|.||.|...||:|.:...||.....|.:|...:...:
  Rat  1378 ----LKVLKAELERLDLVKADKTAIDLELNEKADRDMLASKANRVDLETVAMDLNEMIHSLLLKI 1438

  Fly   485 SLNEKNVLQIIDNLRMTLGIDALELSLKDFREMIERRVQIIAEALQKYMEMTNDDCAAAAGRVKV 549
            :..|.:..:.:.:||..|....::..|...::.||....|:.:.|.:.:....|  :||..:.|:
  Rat  1439 TNYESDWKKSLKHLRKDLNTKLVQSDLNSLKKDIEEVWNIVRKLLLEGLRFDPD--SAAGFKKKL 1501

  Fly   550 MQDLACLACDTTCVMRTVERSKVPSLPNAKGSTGLGPIVTYELGQIRKSGIMGY 603
            .:.:.|::||     |.||....|.|...:...|       .|.:||.:....|
  Rat  1502 FERVKCISCD-----RPVEMMTGPQLITIRNIHG-------GLSRIRPASANSY 1543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nis	NP_608605.1	DUF4795	379..562	CDD:464990	44/184 (24%)
C10h16orf96	XP_063126146.1	None