DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Or22a and Or83a

DIOPT Version :9

Sequence 1:	NP_523453.1	Gene:	Or22a / 33335	FlyBaseID:	FBgn0026398	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_524234.2	Gene:	Or83a / 40648	FlyBaseID:	FBgn0037322	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	101/478 - (21%)
Similarity:	188/478 - (39%)	Gaps:	109/478 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLSKFFPHIKEKPLSERVKSRDAFIYLDR-----VMWSFGWTEPENKRWI---------LPYKLW 51
            |.|.|    ||:.:.:..|.||.|:::.:     .|:.||:.  .|...:         |.|:|:
  Fly     1 MKSTF----KEERIKDDSKRRDLFVFVRQTMCIAAMYPFGYY--VNGSGVLAVLVRFCDLTYELF 59

  Fly    52 LAFVNIVMLILLPISISIEYLHRFKTFSAGEFLSSLEIGVNMYGSSFKCAFTL---IGFKKRQEA 113
            ..||::.:..|...:|.|.|         |:  ..|:..||....:....:|:   :.|::.:..
  Fly    60 NYFVSVHIAGLYICTIYINY---------GQ--GDLDFFVNCLIQTIIYLWTIAMKLYFRRFRPG 113

  Fly   114 KVLLDQLDKRCLSDKE-RSTV-HRYVAMGNFFDI--------LYHIFYSTFVVMNFPYFLLERRH 168
              ||:.:......:.| ||.| ..:|.|...:.:        :|..:..|...:..|....:|..
  Fly   114 --LLNTILSNINDEYETRSAVGFSFVTMAGSYRMSKLWIKTYVYCCYIGTIFWLALPIAYRDRSL 176

  Fly   169 AWRMYFPYIDSDEQFY----------ISSIAECFLMTEAIYMDLCT------DV--CPLISMLMA 215
            ....::|:..:....|          ...:|..|..:..::|.||.      ||  |.|.::| |
  Fly   177 PLACWYPFDYTQPGVYEVVFLLQAMGQIQVAASFASSSGLHMVLCVLISGQYDVLFCSLKNVL-A 240

  Fly   216 RCHISLLKQRLRNLRS----------KPGR-----TEDEYLEEL-----------------TECI 248
            ..:: |:...:..|..          :||:     .|:..|:||                 ..||
  Fly   241 SSYV-LMGANMTELNQLQAEQSAADVEPGQYAYSVEEETPLQELLKVGSSMDFSSAFRLSFVRCI 304

  Fly   249 RDHRLLLDYVDALRPVFSGTIFVQFLLIGTVLGLSMINLMFFST-------FWTGVATCLFMFDV 306
            :.||.:   |.||:.:.|....:.|:.||.|..| |..:.|.||       |...|:...::..|
  Fly   305 QHHRYI---VAALKKIESFYSPIWFVKIGEVTFL-MCLVAFVSTKSTAANSFMRMVSLGQYLLLV 365

  Fly   307 SMETFPFCYLCNMIIDDCQEMSNCLFQSDWTSADRRYKSTLVYFLHNLQQPITLTAGGVFPISMQ 371
            ..|.|..||..:::..:.|.....|::|.|....:..:|..::|:.|.::...||||.:..:::.
  Fly   366 LYELFIICYFADIVFQNSQRCGEALWRSPWQRHLKDVRSDYMFFMLNSRRQFQLTAGKISNLNVD 430

  Fly   372 TNLAMVKLAFSVVTVIKQFNLAE 394
            .....:..|||.:|::::.:..|
  Fly   431 RFRGTITTAFSFLTLLQKMDARE 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Or22a	NP_523453.1	7tm_6	81..381	CDD:251636	74/369 (20%)
Or83a	NP_524234.2	7tm_6	<155..440	CDD:251636	60/290 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21137
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010