DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18132 and TXNDC5

DIOPT Version :9

Sequence 1:NP_608603.1 Gene:CG18132 / 33333 FlyBaseID:FBgn0031345 Length:192 Species:Drosophila melanogaster
Sequence 2:NP_110437.2 Gene:TXNDC5 / 81567 HGNCID:21073 Length:432 Species:Homo sapiens


Alignment Length:122 Identity:38/122 - (31%)
Similarity:63/122 - (51%) Gaps:4/122 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 QSGNVTTITNLSVKARSAD-QCTPGTILKLRVDNFFETTEDGTFFVKFYEPNCMGCHDFETTWTD 90
            ::|...|:|.......:|: :...||:|.|..:||.:|..:|..|:|||.|.|..|.....||.:
Human   298 ETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEE 362

  Fly    91 MA-KSFKSKENICFAELNCKFAKTICNDYELRYEPNLIWLENGEEVQQYDG--DLTS 144
            :: |.|.....:..||::|...:.||:.|.:|..|.|:....|::|.::.|  ||.|
Human   363 LSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDS 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18132NP_608603.1 Thioredoxin_like 51..151 CDD:294274 33/97 (34%)
TXNDC5NP_110437.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 40..63
PDI_a_ERp46 61..164 CDD:239303
ER_PDI_fam 66..432 CDD:273457 38/122 (31%)
PDI_a_ERp46 190..290 CDD:239303
PDI_a_ERp46 323..424 CDD:239303 33/97 (34%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 429..432
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0191
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D522268at2759
OrthoFinder 1 1.000 - - FOG0000934
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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