DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18132 and Txndc16

DIOPT Version :9

Sequence 1:	NP_608603.1	Gene:	CG18132 / 33333	FlyBaseID:	FBgn0031345	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001297463.1	Gene:	Txndc16 / 70561	MGIID:	1917811	Length:	820	Species:	Mus musculus

Alignment Length:	99	Identity:	22/99 - (22%)
Similarity:	36/99 - (36%)	Gaps:	0/99 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LKLRVDNFFETTEDGTFFVKFYEPNCMGCHDFETTWTDMAKSFKSKENICFAELNCKFAKTICND 117
            ::|..:.|..|.......|.||.........|..::.|:|...|.:..|....:||.....||..
Mouse   395 VELTEETFNTTVMTSDSIVLFYATWHAVSMAFLQSYIDVAIKLKGRSTILLTRINCADWSDICTK 459

  Fly   118 YELRYEPNLIWLENGEEVQQYDGDLTSPGIKIFV 151
            ..:...|.:...:.||....|.|.|.:..:..|:
Mouse   460 QNVTAFPVVKLYKEGESPVSYAGMLATKDLLKFI 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18132	NP_608603.1	Thioredoxin_like	51..151	CDD:294274	21/97 (22%)
Txndc16	NP_001297463.1	ER_PDI_fam	65..493	CDD:273457	21/97 (22%)
		PDI_a_family	395..493	CDD:239259	21/97 (22%)
		Thioredoxin_6	534..722	CDD:372755
		Mediates endoplasmic reticulum retention. /evidence=ECO:0000250\|UniProtKB:Q9P2K2	817..820
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900