DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18132 and Erp27

DIOPT Version :10

Sequence 1:NP_608603.1 Gene:CG18132 / 33333 FlyBaseID:FBgn0031345 Length:192 Species:Drosophila melanogaster
Sequence 2:NP_081259.1 Gene:Erp27 / 69187 MGIID:1916437 Length:272 Species:Mus musculus


Alignment Length:59 Identity:18/59 - (30%)
Similarity:23/59 - (38%) Gaps:27/59 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly   143 TSPGIKIFVWEMIRRNETNKSAAKRPYFHTKPIILF-GWFLYA---------GDVISYF 191
            |||..:    |.:||   .:.|||          || |..|:.         |.|:|||
Mouse   171 TSPEYE----ESMRR---YREAAK----------LFQGQILFVLVDSGKRENGKVMSYF 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18132NP_608603.1 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold 51..151 CDD:469754 3/7 (43%)
Erp27NP_081259.1 Thioredoxin_6 64..250 CDD:463999 18/59 (31%)
PDIA3-binding site. /evidence=ECO:0000250|UniProtKB:Q96DN0 230..233
Prevents secretion from ER. /evidence=ECO:0000250|UniProtKB:Q96DN0 269..272
Blue background indicates that the domain is not in the aligned region.

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