DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18132 and Pdia5

DIOPT Version :9

Sequence 1:	NP_608603.1	Gene:	CG18132 / 33333	FlyBaseID:	FBgn0031345	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001014147.1	Gene:	Pdia5 / 360722	RGDID:	1359236	Length:	517	Species:	Rattus norvegicus

Alignment Length:	120	Identity:	32/120 - (26%)
Similarity:	52/120 - (43%)	Gaps:	4/120 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 TILKLRVDNFFETTEDGTF-FVKFYEPNCMGCHDFETTWTDMAKSFKSKENICFAELNCKFAKT- 113
            ::|.|..|||.||.:.... .|.||.|.|..|......:|..|.:||....|..|.::|...|.
  Rat   396 SVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQ 460

  Fly   114 -ICNDYELRYEPNLIWLENGEEVQQYDGDLTSPGIKIFVWEMIRRNETNKSAAKR 167
             :|....::..|...:...|:.|::|:.|.|..|...|: ..:|..:..:...:|
  Rat   461 DLCQQESVKAYPTFHYYHYGKLVEKYESDRTELGFTSFI-RTLREGDLKRLEKRR 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18132	NP_608603.1	Thioredoxin_like	51..151	CDD:294274	29/102 (28%)
Pdia5	NP_001014147.1	PDI_b_PDIR_N	26..137	CDD:239365
		PDI_a_PDIR	150..254	CDD:239295
		ER_PDI_fam	166..501	CDD:273457	30/105 (29%)
		PDI_a_PDIR	275..377	CDD:239295
		PDI_a_PDIR	396..499	CDD:239295	29/102 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255	514..517		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522268at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820