DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18132 and PDILT

DIOPT Version :9

Sequence 1:	NP_608603.1	Gene:	CG18132 / 33333	FlyBaseID:	FBgn0031345	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_777584.1	Gene:	PDILT / 204474	HGNCID:	27338	Length:	584	Species:	Homo sapiens

Alignment Length:	167	Identity:	33/167 - (19%)
Similarity:	65/167 - (38%)	Gaps:	29/167 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SLLIWSAQSDKSLSKQSGNVT----------TITNLSVKARSADQC----TPGTILKLRVDNF-- 60
            |:.|.:..||......|.::|          .::..:.|.:|:::.    ..|.:.:|...||
Human   335 SVQILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNV 399

  Fly    61 --FETTEDGTFFVKFYEPNCMGCHDFETTWTDMAKSFKSKENICFAELNCKFAKTICNDYEL--- 120
              |:..:|  .||.||.|....|........::.:.:::...|..|:::     ...||.:|
Human   400 VVFDKEKD--VFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKID-----VTANDIQLMYL 457

  Fly   121 -RYEPNLIWLENGEEVQQYDGDLTSPGIKIFVWEMIR 156
             ||....::....::...|.|:.|..|...|:...|:
Human   458 DRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIK 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18132	NP_608603.1	Thioredoxin_like	51..151	CDD:294274	22/107 (21%)
PDILT	NP_777584.1	YbbN	46..501	CDD:331940	33/167 (20%)
PDILT	NP_777584.1	Prevents secretion from ER. /evidence=ECO:0000255\|PROSITE-ProRule:PRU10138	581..584
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900