DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18132 and Txndc5

DIOPT Version :9

Sequence 1:	NP_608603.1	Gene:	CG18132 / 33333	FlyBaseID:	FBgn0031345	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_663342.3	Gene:	Txndc5 / 105245	MGIID:	2145316	Length:	417	Species:	Mus musculus

Alignment Length:	98	Identity:	34/98 - (34%)
Similarity:	54/98 - (55%)	Gaps:	3/98 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 GTILKLRVDNFFETTEDGTFFVKFYEPNCMGCHDFETTWTDMA-KSFKSKENICFAELNCKFAKT 113
            ||:|.|...:|.:|...|..|||||.|.|..|.:...||.::: |.|....::..||::|...:.
Mouse   307 GTVLALTEKSFEDTIAQGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCTAERN 371

  Fly   114 ICNDYELRYEPNLIWLENGEEVQQYDG--DLTS 144
            :|:.|.:|..|.|:....||:|.:::|  ||.|
Mouse   372 VCSKYSVRGYPTLLLFRGGEKVGEHNGGRDLDS 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18132	NP_608603.1	Thioredoxin_like	51..151	CDD:294274	33/97 (34%)
Txndc5	NP_663342.3	PDI_a_ERp46	47..150	CDD:239303
		ER_PDI_fam	52..417	CDD:273457	34/98 (35%)
		PDI_a_ERp46	176..276	CDD:239303
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	281..302
		PDI_a_ERp46	308..409	CDD:239303	33/97 (34%)
		Prevents secretion from ER. /evidence=ECO:0000255\|PROSITE-ProRule:PRU10138	414..417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2581
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522268at2759
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.770