DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31661 and AT4G04460

DIOPT Version :9

Sequence 1:	NP_722707.1	Gene:	CG31661 / 33330	FlyBaseID:	FBgn0051661	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_192355.1	Gene:	AT4G04460 / 825776	AraportID:	AT4G04460	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	133/523 - (25%)
Similarity:	210/523 - (40%)	Gaps:	160/523 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VIILLFCLIVF--------------VGGKKVHRFRLERRSHRHHKIPHAHLHLQFRNALRRKYGF 55
            ::.||.|||:.              :|.||       |:..|.:::. :.|.|:.|.:......:
plant    10 LVFLLSCLILISTASCERNGDGTIRIGLKK-------RKLDRSNRLA-SQLFLKNRGSHWSPKHY 66

  Fly    56 TPLRTVNAVNVTSESGKGVVITEPLINSYDTNFFGVVSVG--DQSFTMQFDTGSSDFWVPSSHCR 118
            ..|...||..|            ||.|..|..::|.:::|  .|.||:.||||||:.|:||:.|.
plant    67 FRLNDENADMV------------PLKNYLDAQYYGDITIGTPPQKFTVIFDTGSSNLWIPSTKCY 119

  Fly   119 FCIKTCGNKFFRKSNSKSFRSSGTPFSITYGSGSVKGIVASDNVGFGDLKIQNQ---------GI 174
            ..:....:..::.|.|.|:|.:|.|.||.||:|::.|..::|:|..||:.::.|         ||
plant   120 LSVACYFHSKYKASQSSSYRKNGKPASIRYGTGAISGYFSNDDVKVGDIVVKEQEFIEATSEPGI 184

  Fly   175 GLVNISDSCSVFDGIAGFAFQQLSMTKSVPSFQQMIDQQLVEQPIFSFHLKSGSSD--GGSMILG 237
            ..:     .:.||||.|..|:::|:..|.|.:..|:::.||::|||||.|.....|  ||.::.|
plant   185 TFL-----LAKFDGILGLGFKEISVGNSTPVWYNMVEKGLVKEPIFSFWLNRNPKDPEGGEIVFG 244

  Fly   238 GSNSSLYYGPLTYTNVTEAKYWSFKLDFIAVHGKGSRSSRTGNKAIMDTGTSLIVGPVLEVLYIN 302
            |.:...:.|..|:..||...||.|.:..:.:.||.:.....|..||.|:||||:.||...:..||
plant   245 GVDPKHFKGEHTFVPVTHKGYWQFDMGDLQIAGKPTGYCAKGCSAIADSGTSLLTGPSTVITMIN 309

  Fly   303 KDIGA------------------------------------------------------------ 307
            ..|||
plant   310 HAIGAQGIVSRECKAVVDQYGKTMLNSLLAQEDPKKVCSQIGVCAYDGTQSVSMGIQSVVDDGTS 374

  Fly   308 ---------------------------------------EHNKTYNLYT-VACESIPQLPIIVFG 332
                                                   :|..|.|..: |.|..:..:||:.|.
plant   375 GLLNQAMCSACEMAAVWMESELTQNQTQERILAYAAELCDHIPTQNQQSAVDCGRVSSMPIVTFS 439

  Fly   333 IAGKEFFVKPHTYVIR----YDNFCFSAF--MDMLGLQ--YWILGDAFMRENYVEFDWARRRMGI 389
            |.|:.|.:.|..|:.:    .::.|.|.|  ||:...:  .|||||.||...:..||:.:.|:|.
plant   440 IGGRSFDLTPQDYIFKIGEGVESQCTSGFTAMDIAPPRGPLWILGDIFMGPYHTVFDYGKGRVGF 504

  Fly   390 APA 392
            |.|
plant   505 AKA 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31661	NP_722707.1	pepsin_retropepsin_like	78..391	CDD:299705	114/433 (26%)
CG31661	NP_722707.1	Asp	88..392	CDD:278455	111/424 (26%)
AT4G04460	NP_192355.1	phytepsin	77..506	CDD:133162	115/445 (26%)
		SapB_2	321..353	CDD:367521	0/31 (0%)
		SapB_1	380..417	CDD:368325	1/36 (3%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.980