Protein Alignment CG31661 and PGA4

DIOPT Version :9

• Sequence 1: NP_722707.1
• Gene: CG31661 / 33330
• FlyBaseID: FBgn0051661
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001073276.1
• Gene: PGA4 / 643847
• HGNCID: 8886
• Length: 388
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 133/386 - (34%)
• Similarity: 195/386 - (50%)
• Gaps: 45/386 - (11%)

  Fly    34 HKIPHAHLHLQFRNALRR-------------KYGFTPLRTV----NAVNVTSESGKGVVITEPLI 81
            :|:|     |..:.:|||             |:...|.|..    .|..:..|        :||.
Human    18 YKVP-----LIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDE--------QPLE 69

  Fly    82 NSYDTNFFGVVSVGD--QSFTMQFDTGSSDFWVPSSHCRFCIKTCGNKFFRKSNSKSFRSSGTPF 144
            |..|..:||.:.:|.  |.||:.||||||:.||||.:|.....|..|: |...:|.:::|:....
Human    70 NYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNR-FNPEDSSTYQSTSETV 133

  Fly   145 SITYGSGSVKGIVASDNVGFGDLKIQNQGIGLVNISDSC----SVFDGIAGFAFQQLSMTKSVPS 205
            |||||:||:.||:..|.|..|.:...||..||.......    :.||||.|.|:..:|.:.:.|.
Human   134 SITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPV 198

  Fly   206 FQQMIDQQLVEQPIFSFHLKSGSSDGGSMILGGSNSSLYYGPLTYTNVTEAKYWSFKLDFIAVHG 270
            |..:.:|.||.|.:||.:|.:....|..:|.||.:||.|.|.|.:..||...||...:|.|.::|
Human   199 FDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNG 263

  Fly   271 KGSRSSRTGNKAIMDTGTSLIVGPVLEVLYINKDIGAEHNKTYNLYTVACESIPQLPIIVFGIAG 335
            :....:. |.:||:||||||:.||...:..|..||||..|...:: .|:|.:|..||.|||.|.|
Human   264 EAIACAE-GCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDM-VVSCSAISSLPDIVFTING 326

  Fly   336 KEFFVKPHTYVIRYDNFCFSAFMDM-----LGLQYWILGDAFMRENYVEFDWARRRMGIAP 391
            .::.|.|..|:::.:..|.|.|..|     .| :.|||||.|:|:.:..||.|..::|:||
Human   327 VQYPVPPSAYILQSEGSCISGFQGMNLPTESG-ELWILGDVFIRQYFTVFDRANNQVGLAP 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31661	NP_722707.1	pepsin_retropepsin_like	78..391	CDD:299705	120/323 (37%)
		Asp	88..392	CDD:278455	118/315 (37%)
PGA4	NP_001073276.1	A1_Propeptide	17..45	CDD:311771	6/31 (19%)
		pepsin_A	66..386	CDD:133145	120/323 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020