Protein Alignment CG31661 and Bace

DIOPT Version :9

• Sequence 1: NP_722707.1
• Gene: CG31661 / 33330
• FlyBaseID: FBgn0051661
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 140/411 - (34%)
• Similarity: 213/411 - (51%)
• Gaps: 67/411 - (16%)

  Fly     3 IRVIILLFCLIVFVGGKKVHRFRLERRSH----RHHKIPHAHLHLQFRNALRRKYGFTPLRTVNA 63
            |.|::||..|    ...::||..:.:..:    |.:.:..       ::.||.||....||:|:
  Fly     5 IAVVVLLAAL----ASAELHRVPILKEQNFVKTRQNVLAE-------KSYLRTKYQLPSLRSVD- 57

  Fly    64 VNVTSESGKGVVITEPLINSYDTNFFGVVSVGD--QSFTMQFDTGSSDFWVPSSHCR--FCIKTC 124
                         .|.|.||.:..::|.:|:|.  |||.:.||:|||:.||||:.|:  .|:.
  Fly    58 -------------EEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLT-- 107

  Fly   125 GNKFFRKSNSKSFRSSGTPFSITYGSGSVKGIVASDNVGFGDLKIQNQGIGL------VNISDSC 183
             :..:..|.|.::.::|..|||.||:||:.|.:::|.|....|.||:|....      .|.:|
  Fly   108 -HNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFND-- 169

  Fly   184 SVFDGIAGFAFQQLSMTKSVPSFQQMIDQQLVEQPIFSFHL-KSGSSD-GGSMILGGSNSSLYYG 246
            :.||||.|.|::.|::....|.|..|:.|.||:..:|||:| :.|:|. ||.:|.|||::|||.|
  Fly   170 ANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSG 234

  Fly   247 PLTYTNVTEAKYWSFKLDFIAVHGKGSRSSRTGNKAIMDTGTSLIVGP------VLEVLYINKDI 305
            .|||..::|..||.|.:...::.|   .|.....:||.||||||||.|      :.|:|.:.:|
  Fly   235 ALTYVPISEQGYWQFTMAGSSIDG---YSLCDDCQAIADTGTSLIVAPYNAYITLSEILNVGED- 295

  Fly   306 GAEHNKTYNLYTVACESIPQLPIIVFGIAGKEFFVKPHTYVIRYDNFCFSAFMDMLGLQYWILGD 370
                  .|    :.|.|:..||.:.|.|.|..|.:||..|:|:.|..|.||| :.:|..:|||||
  Fly   296 ------GY----LDCSSVSSLPDVTFNIGGTNFVLKPSAYIIQSDGNCMSAF-EYMGTDFWILGD 349

  Fly   371 AFMRENYVEFDWARRRMGIAP 391
            .|:.:.|.|||....|:|.||
  Fly   350 VFIGQYYTEFDLGNNRIGFAP 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31661	NP_722707.1	pepsin_retropepsin_like	78..391	CDD:299705	123/330 (37%)
		Asp	88..392	CDD:278455	121/322 (38%)
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	123/329 (37%)
		Asp	68..371	CDD:278455	121/323 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455530
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.990