Protein Alignment CG31661 and Ctsd

DIOPT Version :9

• Sequence 1: NP_722707.1
• Gene: CG31661 / 33330
• FlyBaseID: FBgn0051661
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_034113.1
• Gene: Ctsd / 13033
• MGIID: 88562
• Length: 410
• Species: Mus musculus
• Alignment Length: 398
• Identity: 133/398 - (33%)
• Similarity: 192/398 - (48%)
• Gaps: 75/398 - (18%)

  Fly    57 PLRTVNAVNVT-SESG--------KGVV----------ITEP---LINSY-DTNFFGVVSVG--D 96
            |||...::..| :|.|        ||.:          .|||   |:.:| |..::|.:.:|  .
Mouse    25 PLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPP 89

  Fly    97 QSFTMQFDTGSSDFWVPSSHCRFCIKTCG-NKFFRKSNSKSFRSSGTPFSITYGSGSVKGIVASD 160
            |.||:.||||||:.||||.||:.....|. :..:....|.::..:||.|.|.|||||:.|.::.|
Mouse    90 QCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQD 154

  Fly   161 NVGF---------GDLKIQNQ---------GIGLVNISDSCSVFDGIAGFAFQQLSMTKSVPSFQ 207
            .|..         ..:|::.|         ||..|     .:.||||.|..:..:|:...:|.|.
Mouse   155 TVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFV-----AAKFDGILGMGYPHISVNNVLPVFD 214

  Fly   208 QMIDQQLVEQPIFSFHLKSG--SSDGGSMILGGSNSSLYYGPLTYTNVTEAKYWSFKLDFIAVHG 270
            .::.|:||::.||||:|...  ...||.::|||::|..|:|.|:|.|||...||...:|.:.| |
Mouse   215 NLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEV-G 278

  Fly   271 KGSRSSRTGNKAIMDTGTSLIVGPVLEVLYINKDIGA------EHNKTYNLYTVACESIPQLPII 329
            ......:.|.:||:||||||:||||.||..:.|.|||      |       |.:.||.:..||.:
Mouse   279 NELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGE-------YMIPCEKVSSLPTV 336

  Fly   330 VFGIAGKEFFVKPHTYVIRYD----NFCFSAFMDM-----LGLQYWILGDAFMRENYVEFDWARR 385
            ...:.||.:.:.|..|:::..    ..|.|.||.|     .| ..|||||.|:...|..||....
Mouse   337 YLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSG-PLWILGDVFIGSYYTVFDRDNN 400

  Fly   386 RMGIAPAV 393
            |:|.|.||
Mouse   401 RVGFANAV 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31661	NP_722707.1	pepsin_retropepsin_like	78..391	CDD:299705	121/354 (34%)
		Asp	88..392	CDD:278455	117/341 (34%)
Ctsd	NP_034113.1	A1_Propeptide	21..46	CDD:285240	6/20 (30%)
		Cathepsin_D2	73..405	CDD:133157	118/345 (34%)
		Asp	78..407	CDD:278455	117/342 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.980