DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NLaz and APOD

DIOPT Version :9

Sequence 1:	NP_001259867.1	Gene:	NLaz / 33324	FlyBaseID:	FBgn0053126	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001638.1	Gene:	APOD / 347	HGNCID:	612	Length:	189	Species:	Homo sapiens

Alignment Length:	189	Identity:	73/189 - (38%)
Similarity:	101/189 - (53%)	Gaps:	7/189 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLISVVFGAVWVAHAQVPFPGKCPDVKLLDTFDAEAYMGVWYEYAAYPFAFEIGKKCIYANYS 73
            ||||:|.:.|....|..|....||||:..:.:.||...|:|.|||....|..||.| :||.||||
Human     4 LLLLLSALAGLFGAAEGQAFHLGKCPNPPVQENFDVNKYLGRWYEIEKIPTTFENG-RCIQANYS 67

  Fly    74 LIDNSTVSVVNAAINRFTGQPSNVTGQA---KVLGPGQLAVAFYPTQPLTKANYLVLGTDYESYA 135
            |::|..:.|:|..: |..|..:.:.|:|   .:..|.:|.|.|....|  .|.|.:|.||||:||
Human    68 LMENGKIKVLNQEL-RADGTVNQIEGEATPVNLTEPAKLEVKFSWFMP--SAPYWILATDYENYA 129

  Fly   136 VVYSCTSVTPLANFKIVWILTRQREPSAEAVDAARKILEDNDVSQAFLIDTVQKNCPRL 194
            :|||||.:..|.:....|||.|......|.||:.:.||..|::....:..|.|.|||:|
Human   130 LVYSCTCIIQLFHVDFAWILARNPNLPPETVDSLKNILTSNNIDVKKMTVTDQVNCPKL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NLaz	NP_001259867.1	Lipocalin	36..164	CDD:304412	49/130 (38%)
APOD	NP_001638.1	lipocalin_apoD-like	25..182	CDD:381212	60/160 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I7748
eggNOG	1	0.900	-	-		E1_COG3040
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1246
Inparanoid	1	1.050	126	1.000	Inparanoid score	I4708
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47731
OrthoDB	1	1.010	-	-		D1631943at2759
OrthoFinder	1	1.000	-	-		FOG0002020
OrthoInspector	1	1.000	-	-		oto89190
orthoMCL	1	0.900	-	-		OOG6_101844
Panther	1	1.100	-	-	O	PTHR10612
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.880