Protein Alignment CG5556 and PUDP

DIOPT Version :10

• Sequence 1: NP_608595.2
• Gene: CG5556 / 33320
• FlyBaseID: FBgn0031332
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_001129037.1
• Gene: PUDP / 8226
• HGNCID: 16818
• Length: 251
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 71/256 - (27%)
• Similarity: 116/256 - (45%)
• Gaps: 38/256 - (14%)

  Fly    19 PPMCCSPGISYCIFD-----------------------LESAVFDTRHVYKRAVIELAASYNK-- 58
            ||.    .:::.|||                       |:|...||..:|.....|:...|:|
Human     4 PPQ----PVTHLIFDMDGLLLGYTGSIVAAASGESSRGLQSRWTDTERLYSVVFQEICNRYDKKY 64

  Fly    59 --IIPEAVLIKSGPMETAEMAELICRKCDLPVSWESFRFQLNERTSDLIANPTLMPGVERLVTHL 121
              .:...|:.|    :..|.|::|.....||:|.|....:...:..::.....||||.|:|:.||
Human    65 SWDVKSLVMGK----KALEAAQIIIDVLQLPMSKEELVEESQTKLKEVFPTAALMPGAEKLIIHL 125

  Fly   122 GRCCMGLGLITSCSESMYCTKIRDREDFFQNFSSVICADDADLKAPKPEPDVYLIAMRRLG--DA 184
            .:..:...|.||...:.:..|....::||..||.::..||.:::..||:||::|...:|..  .|
Human   126 RKHGIPFALATSSGSASFDMKTSRHKEFFSLFSHIVLGDDPEVQHGKPDPDIFLACAKRFSPPPA 190

  Fly   185 GPDCTLVFDGTPKGVQAATDARLPVVMLAEKDLPCCWSELATLRLETLEEFDPAEFNMPPY 245
            ...| |||:..|.||:||..|.:.|||:.:.:|....:..|||.|.:|::|.|..|.:|.|
Human   191 MEKC-LVFEDAPNGVEAALAAGMQVVMVPDGNLSRDLTTKATLVLNSLQDFQPELFGLPSY 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5556	NP_608595.2	Haloacid Dehalogenase-like Hydrolases	40..249	CDD:473868	64/212 (30%)
PUDP	NP_001129037.1	HAD_AtGPP-like	8..219	CDD:319831	58/215 (27%)