DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a5 and Pebp4

DIOPT Version :9

Sequence 1:	NP_476998.1	Gene:	a5 / 33317	FlyBaseID:	FBgn0011294	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_082836.2	Gene:	Pebp4 / 73523	MGIID:	1920773	Length:	242	Species:	Mus musculus

Alignment Length:	136	Identity:	50/136 - (36%)
Similarity:	74/136 - (54%)	Gaps:	21/136 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LKFQPRLDWNADPESFYTVLMICPDAPNRENPMYRSWLHWLVVNVPGLDI----MKGQPISEYFG 129
            :||...||     .:.|.::|:.||||:|.||:.:.|.||||.|:.|.|:    ::|..:|:|..
Mouse   101 VKFHTALD-----GALYLLVMVDPDAPSRSNPVMKYWRHWLVSNITGADMKSGSIRGNVLSDYSP 160

  Fly   130 PLPPKDSGIQRYLILVYQQSDK---LDFDEKKMELSNAD-GHSNFDVMKFTQKYEMGSPVAGNIF 190
            |.||.::|:.||...||.|.|:   |..:||      || |..|.|  ||.|:|.:..|.....|
Mouse   161 PTPPPETGLHRYQFFVYLQGDRDISLSVEEK------ADLGGWNLD--KFLQQYGLRDPDTSTQF 217

  Fly   191 QSRWDE 196
            .:::||
Mouse   218 MTQFDE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a5	NP_476998.1	PEBP_euk	47..192	CDD:176644	48/130 (37%)
Pebp4	NP_082836.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..50
		PEBP_euk	95..219	CDD:176644	48/130 (37%)
		Important for secretion. /evidence=ECO:0000250\|UniProtKB:Q96S96	210..242		4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1881
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557122at2759
OrthoFinder	1	1.000	-	-		FOG0000438
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X275
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750