DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a5 and MRPL38

DIOPT Version :9

Sequence 1:	NP_476998.1	Gene:	a5 / 33317	FlyBaseID:	FBgn0011294	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_115867.2	Gene:	MRPL38 / 64978	HGNCID:	14033	Length:	380	Species:	Homo sapiens

Alignment Length:	181	Identity:	53/181 - (29%)
Similarity:	83/181 - (45%)	Gaps:	24/181 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PRELLRIKY----DNTIDIEEGKTYTPTELKFQPRLDWNADPESFYTVLMICPDA----PNRENP 100
            ||..|.:.|    |:.:.:..|...||||....|.:.:.|:..|.:|:|:...|.    |:.|
Human   169 PRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQAPEVTYEAEEGSLWTLLLTSLDGHLLEPDAE-- 231

  Fly   101 MYRSWLHWLVVNVPGLDIMKGQPISEYFGPLPPKDSGIQRYLILVYQQSDKLDFDEKK-----ME 160
                :||||:.|:||..:.:||....|..|.|.:.|||.|...|:::|...:||.|..     .:
Human   232 ----YLHWLLTNIPGNRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSEDARPSPCYQ 292

  Fly   161 LSNADGHSNFDVMKFTQKY-EMGSPVAGNIFQSRWDEYVPELMKTLYGVSE 210
            |:    ...|....|.:|: |..:|...:.||.|||:.|..:...|..:.|
Human   293 LA----QRTFRTFDFYKKHQETMTPAGLSFFQCRWDDSVTYIFHQLLDMRE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a5	NP_476998.1	PEBP_euk	47..192	CDD:176644	44/158 (28%)
MRPL38	NP_115867.2	PEBP_euk	171..321	CDD:176644	44/159 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1881
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557122at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820