Protein Alignment CG5397 and Ache

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 700
• Identity: 178/700 - (25%)
• Similarity: 288/700 - (41%)
• Gaps: 157/700 - (22%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTG-- 72
            ||.||||::       ||.|             :|...:||.:..|:  |..::.|.|..:.|
  Rat    17 LLFLLLSLL-------GGGA-------------RAEGREDPQLLVRV--RGGQLRGIRLKAPGGP 59

  Fly    73 IYSFLGMHYAEPPVGPLRYSRPVYKR-LAGDFNATKHGPPCIQ----PHPQF-------PQRIIG 125
            :.:|||:.:||||||..|:..|..|| .:|..:||.....|.|    .:|.|       |.|.:
  Rat    60 VSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNREL- 123

  Fly   126 DEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAA--QYDATPMAQ-RGAIVVAPQYRLGSL 187
            .||||.|||:|| .|..|:..||.:||:.||:..|:::  .||...:|| .|.::|:..||:|:.
  Rat   124 SEDCLYLNVWTP-YPRPTSPTPVLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTF 187

  Fly   188 GIMG-DGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSA 251
            |.:. .|::...||:.:.|...||:||.:.|:.|||:|..|...|..:||||.....:|..|||.
  Rat   188 GFLALPGSRDAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSL 252

  Fly   252 GDVHGVVAMSGTALSQYAMDK--EPVQSVQEVAKINGCPT----GNELEIVNCLRSKSAEDIIKN 310
              .|..|..|||....:|...  |..:....:|::.|||.    ||:.|:::|||::.|:|::.:
  Rat   253 --FHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDH 315

  Fly   311 DDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTK 375
            :..|..:....|         ..|.|.::.:        .:...||..:.:.:|..:.:|.||.|
  Rat   316 EWHVLPQESIFR---------FSFVPVVDGD--------FLSDTPEALINTGDFQDLQVLVGVVK 363

  Fly   376 HETANSVTVETIEKVFG------------SAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPG 428
            .|.:..:       |:|            |..|||..:                  :|..|:...
  Rat   364 DEGSYFL-------VYGVPGFSKDNESLISRAQFLAGV------------------RIGVPQASD 403

  Fly   429 LTSVLTPTLQDVWKVPQ-ALNVDQVLSKVVESTTDVLFNLP-AVLTTQVWSRLAPAFMYSFEYNG 491
            |.:.........|..|: ..::...:|.||.....|   .| |.|..::.::.|..:.|.||:..
  Rat   404 LAAEAVVLHYTDWLHPEDPAHLRDAMSAVVGDHNVV---CPVAQLAGRLAAQGARVYAYIFEHRA 465

  Fly   492 TKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLID 556
            :......:: |:|              ||.||.:      |||.|::.:...:.|:......|:.
  Rat   466 STLTWPLWM-GVP--------------HGYEIEF------IFGLPLDPSLNYTVEERIFAQRLMK 509

  Fly   557 LLVKFA---NKDKEEGGKSSIFQSVTGKATPFIKIDTK-LQTSNDFRFCELSVLGASLSPLSSTS 617
            ....||   :.:.....||..:...|..|..::.::.| |:.....|               :.:
  Rat   510 YWTNFARTGDPNDPRDSKSPRWPPYTTAAQQYVSLNLKPLEVRRGLR---------------AQT 559

  Fly   618 CAGLGNLLGQLGSLGGGLGGTLGGVGSTLGLGGNGGGGKRGG--LGLGIL 665
            ||.....|.:|      |..|...|..|.....:|....|.|  |.|.:|
  Rat   560 CAFWNRFLPKL------LSATATEVPCTCPSPAHGEAAPRPGPALSLSLL 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	153/592 (26%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	155/612 (25%)