DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5397 and Ces2j

DIOPT Version :9

Sequence 1:	NP_001259865.1	Gene:	CG5397 / 33313	FlyBaseID:	FBgn0031327	Length:	665	Species:	Drosophila melanogaster
Sequence 2:	XP_038953911.1	Gene:	Ces2j / 685645	RGDID:	1591368	Length:	576	Species:	Rattus norvegicus

Alignment Length:	547	Identity:	146/547 - (26%)
Similarity:	221/547 - (40%)	Gaps:	140/547 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RNPSTGIYSFLGMHYAEPPVGPLRYSRPV-YKRLAGDFNATKHGPPCIQPH------------PQ 118
            ::..:||::|||:.:|:|||||||::.|. .:..:|..:||.....|:|..            .:
  Rat    69 KDTKSGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQTAMMNLEGMKETELTK 133

  Fly   119 FPQRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRGAIV-VAPQY 182
            .|.    .||||.||:|.|....|.:.|||.||||.||...|||:..||:.:|....|| |:.||
  Rat   134 LPM----SEDCLYLNIYVPAHAHEDSNLPVMVWIHGGGLVGGSASMNDASTLAATEEIVIVSIQY 194

  Fly   183 RLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPT 247
            |||.||....|.:...||....|..||||||...|:|||||...|...|..:|..|.....:||.
  Rat   195 RLGVLGFFSTGDQHARGNWGYLDQMAALRWVQQNIAYFGGNRDSVTIFGVSAGGTSVSSHVVSPM 259

  Fly   248 SRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDD 312
            |:  |..|..:..||.||....:........:.||.::||...:...::.|||:||.::|
  Rat   260 SK--GLFHRAIMQSGVALLPGLISDTSEVVYKTVANLSGCEASDSEALIRCLRAKSKQEI----- 317

  Fly   313 KVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHE 377
                  ||...:.|.:.|.|          ||:.||.    .|::.|.|.:|..:|.:.||...|
  Rat   318 ------LAINQVFKMIPGVV----------DGKFLPK----HPQELLASKDFHPVPSIIGVNTDE 362

  Fly   378 TA-------------NSVTVETIEKVFGSA---------------EQFLGSLSDSLNKLTSFLKI 414
            ..             |::|.||:......|               |:::|...|:
  Rat   363 CGWGVPTILGLYHIINNITRETLPAALKIAAAQMMLPPECIDLIMEEYMGDTEDA---------- 417

  Fly   415 DKLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRL 479
                                .|||..:|               |...|.:|.:||:.........
  Rat   418 --------------------ETLQAQFK---------------EMLGDFIFVIPALQVAHFQRSQ 447

  Fly   480 APAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKP--ETVGHGDEIGYMFDANDIFGNPMEETRL 542
            ||.:.|.|::.      ::|:|.:         :|  ....|||:..::| .:..:|...:   |
  Rat   448 APVYFYEFQHL------LSFIKQV---------RPFYPKADHGDDTVFVF-GSYFWGMTFD---L 493

  Fly   543 TSAEDLKVRNNLIDLLVKFANKDKEEG 569
            |..|:| ::..::.....||......|
  Rat   494 TEEEEL-LKRRVMKYWANFARTGNPNG 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	146/547 (27%)
CG5397	NP_001259865.1	Aes	82..>261	CDD:223730	74/192 (39%)
Ces2j	XP_038953911.1	COesterase	50..555	CDD:395084	146/547 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910