Protein Alignment CG5397 and Aadac

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_075872.1
• Gene: Aadac / 67758
• MGIID: 1915008
• Length: 398
• Species: Mus musculus
• Alignment Length: 342
• Identity: 66/342 - (19%)
• Similarity: 107/342 - (31%)
• Gaps: 125/342 - (36%)

  Fly   110 PPCIQPHPQFPQRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMA--- 171
            ||....|....:...   |.:.:.:|.|:.........:| :||.||:..||||.:....::
Mouse    71 PPTSDEHVTVMETAF---DSVPVRIYIPKRKSMALRRGLF-YIHGGGWCLGSAAHFSYDTLSRWT 131

  Fly   172 --QRGAIVVAPQYRLGSLGIMGDGTKQFDGNLAMFDLAAALRWV--TDYISYFGGNPKQVQAIGH 232
              :..|:||:..|   .|.......:||:      |:..:|||.  .|.:..:|.:|::|...|.
Mouse   132 AHKLDAVVVSTDY---GLAPKHHFPRQFE------DVYRSLRWFLQEDVLEKYGVDPRRVGVSGD 187

  Fly   233 GSG----AASAMYLSMSP-----------------------TSRSAGDVHGV------------- 257
            .:|    ||....|...|                       .|:..|....|
Mouse   188 SAGGNLAAAVTQQLIQDPDVKIKLKVQALIYPALQALDTNVPSQQEGSHFPVLTRSLMVRFWSEY 252

  Fly   258 ----------------VAMSGTALSQYA--------------MDKEPVQSVQEVAK-------IN 285
                            |.|..:.|.|:.              :.|.|.....|:|:       :.
Mouse   253 FTTDRGLEKAMLLNQHVPMESSHLLQFVNWSSLLPERYKKSPVYKNPTPGSSELAQKYPGFIDVK 317

  Fly   286 GCP---TGNELE------IVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGF---QPHI 338
            .||   ..|.|.      |:.|     ..|::::|..:..:||.          |||.   ..|:
Mouse   318 ACPLLANDNILHHLPKTYIITC-----QYDVLRDDGLMYVKRLQ----------NVGVHVTHHHV 367

  Fly   339 ESEDDGR-ALPSLIVGE 354
            |....|. :.|.|.:.|
Mouse   368 EDGFHGTFSFPGLKLSE 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	66/342 (19%)
Aadac	NP_075872.1	Abhydrolase_3	106..356	CDD:400284	50/264 (19%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		1/1 (100%)