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Protein Alignment CG5397 and BCHE

DIOPT Version :9

Sequence 1:	NP_001259865.1	Gene:	CG5397 / 33313	FlyBaseID:	FBgn0031327	Length:	665	Species:	Drosophila melanogaster
Sequence 2:	NP_000046.1	Gene:	BCHE / 590	HGNCID:	983	Length:	602	Species:	Homo sapiens

Alignment Length:	633	Identity:	180/633 - (28%)
Similarity:	273/633 - (43%)	Gaps:	143/633 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTG- 72
            |::.:......|..|...|.:|                .:|.:|.|   .::.:|.|......|
Human     6 TIICIRFLFWFLLLCMLIGKSH----------------TEDDIIIA---TKNGKVRGMNLTVFGG 51

  Fly    73 -IYSFLGMHYAEPPVGPLRYSRPVYKRLAGD-FNATKHGPPCIQPHPQ-FPQRIIG--------- 125
             :.:|||:.||:||:|.||:.:|.......| :||||:...|.|...| ||    |
Human    52 TVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFP----GFHGSEMWNP 112

  Fly   126 ----DEDCLLLNVYTP-QMPDETTGLPVFVWIHPGGYRYGSAA--QYDATPMAQ-RGAIVVAPQY 182
                .||||.|||:.| ..|...|   |.:||:.||::.|:::  .||...:|: ...|||:..|
Human   113 NTDLSEDCLYLNVWIPAPKPKNAT---VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNY 174

  Fly   183 RLGSLGIMG-DGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSP 246
            |:|:||.:. .|..:..||:.:||...||:||...|:.||||||.|...|..:||||.....:||
Human   175 RVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSP 239

  Fly   247 TSRSAGDVHGVVAMSGTALSQYAMDK--EPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIK 309
            .|.|.  ....:..||:..:.:|:..  |.......:||:.||...||.||:.|||:|..::|:.
Human   240 GSHSL--FTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILL 302

  Fly   310 NDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVT 374
            |:..|         :..|...:|.|.|.:    ||..|..:    |:..|:...|....:|.||.
Human   303 NEAFV---------VPYGTPLSVNFGPTV----DGDFLTDM----PDILLELGQFKKTQILVGVN 350

  Fly   375 KHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLT-----SVL- 433
            |.|       .|...|:|:.    |...|:.:.:|.     |...:..|...||::     |:|
Human   351 KDE-------GTAFLVYGAP----GFSKDNNSIITR-----KEFQEGLKIFFPGVSEFGKESILF 399

  Fly   434 --TPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLA-PAFMYSFEYNGTKSK 495
              |..:.|  :.|:  |..:.|..||   .|..|..||:..|:.:|... .||.|.||:..:|
Human   400 HYTDWVDD--QRPE--NYREALGDVV---GDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSK-- 455

  Fly   496 GINFLKGLPIVSETAHDKPETVG--HGDEIGYMFDANDIFGNPME-ETRLTSAEDLKVRN----- 552
                   ||        .||.:|  ||.||.:      :||.|:| ....|.||::..|:
Human   456 -------LP--------WPEWMGVMHGYEIEF------VFGLPLERRDNYTKAEEILSRSIVKRW 499

  Fly   553 -NLIDLLVKFANKDKEEGGKSS--IFQSVTGK----ATPFIKIDTKLQ 593
             |    ..|:.|.::.:...:|  :|:|...|    .|...:|.|||:
Human   500 AN----FAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLR 543

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.