Protein Alignment CG5397 and NCEH1

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001139748.2
• Gene: NCEH1 / 57552
• HGNCID: 29260
• Length: 416
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 68/323 - (21%)
• Similarity: 110/323 - (34%)
• Gaps: 128/323 - (39%)

  Fly   126 DEDCLLLNVYT-PQMPDETTGLPVFVWIHPGGYRYGSAA----------QYD--ATPMAQR-GAI 176
            |.|.:.:.|:. |..|:|.....| |:||.||:...||:          .||  .|.||:. .|:
Human    86 DFDGVEVRVFEGPPKPEEPLKRSV-VYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAV 149

  Fly   177 VVAPQYRL---------------------------------GSLGIMGDGTKQFDGNLA-----M 203
            :|:.:|||                                 |.:.|.||..   .||||     .
Human   150 IVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSA---GGNLAAALGQQ 211

  Fly   204 FDLAAALR------------------------------------WVTDYISYFGGNPKQVQAI-- 230
            |...|:|:                                    .|..::.||.||...|||:
Human   212 FTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIV 276

  Fly   231 -GHGS---GAASAM-----YLSMSPTSRSAGDVHGVVAMSGTA-----LSQYAMDKEPVQSVQEV 281
             .|.|   ..|:|:     :.|:.|.|.:. :...||..:|.|     |.| .:|......:.:.
Human   277 NNHTSLDVEEAAAVRARLNWTSLLPASFTK-NYKPVVQTTGNARIVQELPQ-LLDARSAPLIADQ 339

  Fly   282 AKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDG 344
            |.:...|   :..|:.|     ..|::::|..:..:||.          :.|.:..::..:||
Human   340 AVLQLLP---KTYILTC-----EHDVLRDDGIMYAKRLE----------SAGVEVTLDHFEDG 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	68/323 (21%)
NCEH1	NP_001139748.2	Abhydrolase_3	109..389	CDD:400284	62/300 (21%)