Protein Alignment CG5397 and Ces2h

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 541
• Identity: 154/541 - (28%)
• Similarity: 236/541 - (43%)
• Gaps: 92/541 - (17%)

  Fly    72 GIYSFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQ---------------PHPQFP 120
            |::||||:.:|:|||||||::.| ..:...|..:.|.|...|:|               ..|.||
Mouse    53 GVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFP 117

  Fly   121 QRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPM-AQRGAIVVAPQYRL 184
            .    .||||.||:|.|....|.:.|||.||||.|....|.|:.||.:.: |....:||..||||
Mouse   118 M----SEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDGSMLAAMENVVVVTIQYRL 178

  Fly   185 GSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSR 249
            |.||....|.::..||....|..|||||:...|:||||||.:|...|..:|..|...|.:||.|:
Mouse   179 GVLGFFSTGDERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQ 243

  Fly   250 SAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKV 314
              |...|.:..||.||....:........|.||.::||...:...:|||||.||.|:|
Mouse   244 --GLFRGAIMESGVALISSLISVSSDVVYQTVANLSGCEQVDSEALVNCLRGKSEEEI------- 299

  Fly   315 QTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETA 379
                :|.....|.:.|.|          ||..||.    .|::.:.|::|..:|.:.||...|..
Mouse   300 ----MAINKAFKIIPGIV----------DGIFLPR----HPQELMASADFHPVPSIIGVNNDEYG 346

  Fly   380 NSV--TVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWK 442
            ..:  ::..|:...|...|.:.::            :.:...|:..|  |.::.:|........:
Mouse   347 WIIPSSMSMIDSKKGMDRQMVQAI------------LQRRATQMMWP--PEVSDLLMEEYMGDNE 397

  Fly   443 VPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGLPIVS 507
            .||.|.|     :..|...|..|.:||:...|.....||.|.|.|::..      :|.|.    |
Mouse   398 DPQFLQV-----QFKEMMKDFTFVIPALQVAQFQRSHAPVFFYEFQHRP------SFFKD----S 447

  Fly   508 ETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLIDLLVKFAN--KDKEEGG 570
            :.:|.|.:   |||||.::|  ...:|.  .:...|..|:|..|.    ::..:||  :.:....
Mouse   448 KPSHVKAD---HGDEILFIF--RSFWGG--TQVDFTEEEELLSRR----MMKYWANFARQRNPNS 501

  Fly   571 KSSIFQSVTGKATPFIKIDTK 591
            :...:..:..:...::::||:
Mouse   502 EGLPYWPMFDQDEQYLQLDTQ 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	154/541 (28%)
		Aes	82..>261	CDD:223730	74/195 (38%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	154/541 (28%)
		Aes	<127..>230	CDD:223730	43/102 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910