Protein Alignment CG5397 and Nlg4

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 871
• Identity: 193/871 - (22%)
• Similarity: 298/871 - (34%)
• Gaps: 312/871 - (35%)

  Fly    10 LLLLLLSVVILA--SCKSGGDAHVRVKRIVGGK--QSKAPPVDDPVIFARLFDRDARVEGFRNPS 70
            |.||||..|:::  .|.....|.:.....:|.:  |::         :.||......::.||. .
  Fly    10 LRLLLLPTVLISWMHCAGASTADIYKGARLGHRIVQTR---------YGRLHGLILPLDSFRF-L 64

  Fly    71 TGIYSFLGMHYAEPPVGPLRYSRPVYKRLAGDFN----ATKHGPPCIQPHP-------------- 117
            ..:..|||:.||.||....|:| |.  |....::    :.|:.|.|.|..|
  Fly    65 RSVEVFLGVPYATPPTKQNRFS-PT--RAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPK 126

  Fly   118 ---QFPQRII-----GDEDCLLLNVYTP-QMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQR 173
               ::.:|::     ..||||.|||::| ........|||.|:||...:.:.|...||.:.:|..
  Fly   127 GRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASY 191

  Fly   174 GAIVVAP-QYRLGSLGIMGDGTKQFD----GNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHG 233
            |.:||.. .||||.||.:........    .|..:.|..|||.|:...|..|||:|..|...|||
  Fly   192 GEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHG 256

  Fly   234 SGAASAMYLSMSPTSRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNEL----- 293
            :|||...||..||| ...|..|..:.|||:|.|.:|:.::||....::||...|...:::
  Fly   257 TGAACINYLMTSPT-MVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHE 320

  Fly   294 EIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQ 358
            :||:|||....||:...|  :|....        ||   .|.|.:    ||      :|..|..
  Fly   321 QIVDCLRDVPLEDLYLAD--IQAPNF--------LT---SFGPSV----DG------VVIRPGH- 361

  Fly   359 LKSSNFSGIPLLTGVTKHETANSVTVETI------------------EKVFGSAEQFLGSLSDSL 405
               ||.....|:...::..:|:|....:.                  ...||.. .|.||.:.::
  Fly   362 ---SNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGG-YFGGSGAGTM 422

  Fly   406 NKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWK----------------------VPQALN 448
            |....:   |.|.|.:              |.:.:|:                      |..|.|
  Fly   423 NMGGHY---DVLFGVV--------------TGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYN 470

  Fly   449 --VDQVLSKVVESTT---------------------DVLFNLPAVLTTQVWSRLAP--------- 481
              ::::...:|...|                     |..|..|.|....:.:..:|
  Fly   471 YHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTA 535

  Fly   482 ---------------------AFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPETVG--HGDEI 523
                                 .:.|.|:|. ||.                .|.|:.:|  ||:::
  Fly   536 GSPGANAAASTSAGSTQPSGRCYFYVFDYQ-TKD----------------GDYPQRMGTVHGEDL 583

  Fly   524 GYMFDANDIFGNPM-------------EETRLTSAEDLKVRNNLIDLLVKFANKDKEEGGKSSI- 574
            .|      |||.|:             .||.|:.|..:...|     ..:..|.::.....||:
  Fly   584 PY------IFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTN-----FARTGNPNEHHRQDSSLP 637

  Fly   575 -------FQSVTGK-----ATPFIKIDTKLQTSNDFRFCELSV---------------------- 605
                   |:|:|.:     ...:::|..|.:..|.||..:||:
  Fly   638 VSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHNL 702

  Fly   606 ------------------------LGASLSPLSSTSCAGLGNLLGQL-GSLGGGLGGT--LGGV- 642
                                    .|||.|..||:|.:.|..:..|| ...|.||.|:  |.|:
  Fly   703 FRNHDDMDLYEGPVKPDPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGIL 767

  Fly   643 GST-----------LGLGGN--GGGG 655
            |.|           :.:|||  ..||
  Fly   768 GVTTVEPNNMYTTCIPIGGNYSSSGG 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	156/708 (22%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	161/724 (22%)