Protein Alignment CG5397 and Nlg3

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 145/662 - (21%)
• Similarity: 243/662 - (36%)
• Gaps: 182/662 - (27%)

  Fly    73 IYSFLGMHYAEPPVGPLRYSRPVYKRL-AGDFNATKHGPPCIQPHP-----------------QF 119
            :.::.|:.||.||||.||:..||...: :|...|.:..|.|.|..|                 ::
  Fly   180 VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEY 244

  Fly   120 PQRII-----GDEDCLLLNVYTP----------------------------------QMPDETTG 145
            .:|::     ..||||.||:|.|                                  .....:.|
  Fly   245 LKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAG 309

  Fly   146 ------LPVFVWIHPGGYRYGSAAQYDATPMAQRGAI-VVAPQYRLGSLGIMGDGTKQFD---GN 200
                  .||.|::|...|.:.|...||.:.:|..|.| ||...||||.||.:...|.::.   .|
  Fly   310 SGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPAN 374

  Fly   201 LAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTAL 265
            ..:.|:.|||.|:.:.|:.|||:|..:...|||:|||...:|..|.........:..:.|||:.|
  Fly   375 YGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGL 439

  Fly   266 SQYAMDKEPVQSVQEVAKINGCPTG-NELEIVNCLRSKSAED----------------------I 307
            :.:::...|.:....||....|.:. ....::.|||.|:.:.                      :
  Fly   440 APWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVV 504

  Fly   308 IKNDDKV---------QTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPE-----QQ 358
            |...|.|         |.:..|..|...||.|..|.     :...|...|    |:.|     ::
  Fly   505 IDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGI-----AAAGGWGTP----GQLENIVLMRK 560

  Fly   359 LKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAK 423
            ...:..|...|:.|||:.|...|         |.|.:...|..:|..:::        |...:..
  Fly   561 TAINKLSRYDLMAGVTRAEAFFS---------FNSGDVQYGIEADRRSRI--------LKAYVRN 608

  Fly   424 PELPGLTSVLTPTLQDV--WKVP--QALNV-DQVLSKVVESTTDVLFNLPAVLTTQVWSR-LAPA 482
            .....|..:....:.:.  |:.|  ..:|: |:.|    |:.:|.....||..|..:.|. ...:
  Fly   609 TYTFHLNEIFATIVNEYTDWERPVQHPINIRDETL----EALSDAQVVAPAAQTVDLHSADHRNS 669

  Fly   483 FMYSFEYNGTKSKGINFLKGLPIVSETAH-DKPETVG--HGDEIGYMFDANDIFGNPMEETRLTS 544
            ::|.|:|                  :|.. |.|:..|  ||:::.|:|.| .:.|.....||..:
  Fly   670 YLYVFDY------------------QTRFGDYPQRQGCIHGEDLPYIFGA-PLVGGFNHFTRNYT 715

  Fly   545 AEDLKVRNNLI---DLLVKFANKDK----EEGGKS----------SIFQSVTGKATPFIKIDTKL 592
            ..::.:...::   ...|:..|.::    |.|.:.          :.::||..|   ::..|||.
  Fly   716 KTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKK---YLNFDTKP 777

  Fly   593 QTSNDFRFCELS 604
            :..|.:|...||
  Fly   778 KLKNHYRAHRLS 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	142/655 (22%)
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	145/662 (22%)