Protein Alignment CG5397 and Nlg3

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 641
• Identity: 164/641 - (25%)
• Similarity: 249/641 - (38%)
• Gaps: 189/641 - (29%)

  Fly    73 IYSFLGMHYAEPPVGPLRYSRPVYKRL-AGDFNATKHGPPCIQPHP-----------------QF 119
            :.:|.|:.||.||||.||:..||...| :|...|.:..|.|.|..|                 ::
Mosquito    88 VEAFRGVPYASPPVGNLRFMPPVTGALWSGVKKADRFSPVCPQRLPDIYNETAALERMPRGRLEY 152

  Fly   120 PQRII-----GDEDCLLLNVYTP-----QMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRG 174
            .:|::     ..||||.||:|.|     :....|:...|.|::|...|.:.|...||.:.:|..|
Mosquito   153 LRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSSTSKYAVVVFVHGESYEWNSGNPYDGSVLASYG 217

  Fly   175 AI-VVAPQYRLGSLGIMGDGTKQFD---GNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSG 235
            .| ||...||||.||.:.....:|.   .|..:.|:.|||.|:.:.|..|||:||.|...|||:|
Mosquito   218 QILVVTINYRLGILGFLNANVDRFSKAPANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTG 282

  Fly   236 AASAMYLSMSPTSRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVA-KINGCPTGNELEIVNCL 299
            ||...:|..|.........|..:.|||:.|:.:::..||.:....|: .:|..|......::.||
Mosquito   283 AACVHFLIASAAVPEGLLFHRAIMMSGSGLAPWSLVGEPAKFAAYVSHHVNCSPDLPHQLLLKCL 347

  Fly   300 RSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQ--LKSS 362
            |.|..|||:....:...            .|| .|.|.:    ||..:.:   ||.:|.  ...|
Mosquito   348 RDKPLEDILSTSVRAPD------------FGN-AFGPSV----DGVVIDT---GEIQQMDGTHYS 392

  Fly   363 NFSGIPLLTGVTK--HETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPE 425
            ::||.|..|..:.  |.|.|::....:.|:             ::|||:   |.|.|.| :.:.|
Mosquito   393 DYSGNPAATKPSAHIHNTLNTINAILLRKL-------------AINKLS---KYDLLVG-VTRAE 440

  Fly   426 LPGLTSVLTPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQV-----WSR------- 478
                 :......:||....:|....::|...|.||..  |:|..:|.|.|     |.|
Mosquito   441 -----AYFAFNSEDVQYGIEADRRAKILKNYVRSTYS--FHLNEILATIVNEYTDWERPVQHPIN 498

  Fly   479 --------------LAPA--------------FMYSFEYNGTKSKGINFLKGLPIVSETAHDKPE 515
                          :|||              |:|.|:|. ||                ..|.|:
Mosquito   499 IRDETLEALSDARIVAPAVQTADLHSADHRNSFLYVFDYQ-TK----------------FGDFPQ 546

  Fly   516 TVG--HGDEIGYMFDA-----------------------------NDI-FGNPMEETRLTSAEDL 548
            ..|  ||:::.|:|.|                             |.| .|||.|:     .|:.
Mosquito   547 RQGCIHGEDLPYLFGAPLVGGFNHFTRNYTKSEIALSEAVMIYWSNFIRTGNPNEQ-----LEND 606

  Fly   549 KVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRFCELS 604
            .||:.     .:|.|.:      .:.::||..|   ::.:|||.:..|.:|...||
Mosquito   607 HVRDR-----TRFKNIE------WTPYESVHKK---YLNLDTKPKLKNHYRAHRLS 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	161/634 (25%)
Nlg3	XP_061500330.1	None