Protein Alignment CG5397 and Nceh1

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_848887.1
• Gene: Nceh1 / 320024
• MGIID: 2443191
• Length: 408
• Species: Mus musculus
• Alignment Length: 395
• Identity: 80/395 - (20%)
• Similarity: 138/395 - (34%)
• Gaps: 142/395 - (35%)

  Fly    47 VDDPVIFARLFDRDARVEGFRNPSTGIYSFLGMHYAEPPVGPLRYSRPVYKRLAGDFNATKHGPP 111
            |.||   .:|...||...|.:..|..|:| ||::               :..:|.:|..|..|..
Mouse    27 VSDP---WKLMLLDATFRGAQQVSNLIHS-LGLN---------------HHLIALNFIITSFGKQ 72

  Fly   112 CIQPHPQFPQRIIG-DEDCLLLNVY--TPQMPDETTGLPVFVWIHPGGYRYGSA--AQYD--ATP 169
            ..:..|:.  ::.. |.|.:.:.|:  :|: |:|.....| ::||.||:...||  :.||  .|.
Mouse    73 SARSSPKV--KVTDTDFDGVEVRVFEGSPK-PEEPLRRSV-IYIHGGGWALASAKISYYDQLCTT 133

  Fly   170 MAQR-GAIVVAPQYRL---------------------------------GSLGIMGDGTKQFDGN 200
            ||:. .|::|:.:|||                                 |.:||.||..   .||
Mouse   134 MAEELNAVIVSIEYRLVPQVYFPEQIHDVIRATKYFLQPEVLDKYKVDPGRVGISGDSA---GGN 195

  Fly   201 LA-----MFDLAAALR------------------------------------WVTDYISYFGGNP 224
            ||     .|...|:|:                                    .|..::.||.||.
Mouse   196 LAAALGQQFTYVASLKNKLKLQALVYPVLQALDFNTPSYQQSMNTPILPRHVMVRYWLDYFKGNY 260

  Fly   225 KQVQAI---GHGS---GAASAM-----YLSMSPTSRSAGDVHGVVAMSGTALSQYAMDKEPVQSV 278
            ..|:|:   .|.|   ..|:|:     :.|:.|:|         :..:...:.|...:...||.:
Mouse   261 DFVEAMIVNNHTSLDVERAAALRARLDWTSLLPSS---------IKKNYKPIMQTTGNARIVQEI 316

  Fly   279 QEVAKINGCPTGNELEIVNCLRS----KSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIE 339
            .::......|...|.|::..|..    ....|::::|..:..:||.          :.|....::
Mouse   317 PQLLDAAASPLIAEQEVLEALPKTYILTCEHDVLRDDGIMYAKRLE----------SAGVNVTLD 371

  Fly   340 SEDDG 344
            ..:||
Mouse   372 HFEDG 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	79/394 (20%)
Nceh1	NP_848887.1	Abhydrolase_3	109..381	CDD:400284	57/291 (20%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	113..115		1/1 (100%)