Protein Alignment CG5397 and Ces1e

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_113753.2
• Gene: Ces1e / 29225
• RGDID: 621508
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 168/599 - (28%)
• Similarity: 254/599 - (42%)
• Gaps: 129/599 - (21%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIY 74
            :.|..|.:|.||:..:            ||..|..|.||  .:..::..:...:|||..|   :.
  Rat     1 MCLYALILVFLAAFTA------------GGHPSSLPVVD--TLQGKVLGKYVSLEGFTQP---VA 48

  Fly    75 SFLGMHYAEPPVGPLRYSRP-------VYKRLAGDFNATKHGPPCIQPHPQFPQRIIGD------ 126
            .|||:.:|:||:|.||::.|       ..|      |.|.:.|.|.| .|...| |:.|
  Rat    49 VFLGVPFAKPPLGSLRFAPPQPAEPWSFVK------NTTSYPPMCSQ-DPVAGQ-IVNDLLTNRE 105

  Fly   127 --------EDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMA-QRGAIVVAPQY 182
                    ||||.||:|||....:...|||.||||.||...|.|:.||...:: ....:||..||
  Rat   106 ENISLQFSEDCLYLNIYTPADLTKRDRLPVMVWIHGGGLVLGGASTYDGLALSTHENVVVVVIQY 170

  Fly   183 RLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPT 247
            |||..|....|.:...||....|..|||.||.|.|..|||:|..|...|..:|..|...|.:||.
  Rat   171 RLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIDNFGGDPGSVTIFGESAGGESVSVLVLSPL 235

  Fly   248 SRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDD 312
            :::.  .|..::.||.||:...:.|......:::|.::||.:.....:|:|||.|:.|::::...
  Rat   236 AKNL--FHKAISESGVALTAGLVKKNTRPLAEKIAVVSGCKSTTSAAMVHCLRQKTEEELLETTL 298

  Fly   313 KVQTERLAGRALVKGLTGNV-GFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKH 376
            |:....|       .|.|:. ...|.:.:..||..||.:    ||:.|...:|:.:|.:.|:.|.
  Rat   299 KLNLFSL-------DLHGDSRQSYPFVPTVLDGVVLPKM----PEEILAEKDFNTVPYIVGINKQ 352

  Fly   377 ETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVW 441
            |             ||      ..|...:|...|.:|:|.:|.    ..|...:|.|....::.
  Rat   353 E-------------FG------WILPTMMNYPPSDMKLDPMTA----TSLLKKSSFLLNLPEEA- 393

  Fly   442 KVPQAL------------NVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPA--FMYSFEYNGT 492
             :|.|:            |.||:|    |...||:|.:|:|:.:: ..|.|.|  :||.|:|..:
  Rat   394 -IPVAVEKYLRHTDDPDRNKDQLL----ELIGDVIFGVPSVIVSR-GHRDAGARTYMYEFQYRPS 452

  Fly   493 KSKGINFLKGLPIVSETAHDKPETV--GHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLI 555
            .|..:               ||.||  .|||||..:|.|..:.|.       ||.|::.:...::
  Rat   453 FSSKM---------------KPSTVVGDHGDEIYSVFGAPILRGG-------TSKEEINLSKMMM 495

  Fly   556 DLLVKFANKDKEEG 569
            .....||......|
  Rat   496 KFWANFARNGNPNG 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	158/561 (28%)
Ces1e	NP_113753.2	COesterase	24..545	CDD:395084	160/564 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561