Protein Alignment CG5397 and Ces4a

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 568
• Identity: 155/568 - (27%)
• Similarity: 236/568 - (41%)
• Gaps: 112/568 - (19%)

  Fly    71 TGIYSFLGMHYAEPPVGPLRYSRPVYK-RLAGDFNATKHGPPCIQ------------PHPQFPQR 122
            |.|..|||:.:::||||..|::.|... ...|..:||.:.|.|:|            ...|: :.
  Rat    53 TPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQY-EW 116

  Fly   123 IIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRGAIV-VAPQYRLGS 186
            :...||||.||||.|.:......|||.||...|.:..|||:.|:.:.:|.||.:| |..|||||.
  Rat   117 LHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFLQYRLGI 181

  Fly   187 LGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSA 251
            ||....|.....||..:.|..||||||.:.|..|||:|..|...|..:||.|...|.|||.::
  Rat   182 LGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQ-- 244

  Fly   252 GDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQT 316
            |..|..::.||||:.:..:..:|::|.:::|.:.||...:...:|.||::..||.::....|:..
  Rat   245 GLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKIMVKCLKALPAEKVMLVSKKMTF 309

  Fly   317 ERLAGRALVKGLTGNVGFQPHIESED---------DGRALPSLIVGEPEQQLKSSNFSGIPLLTG 372
            .|.               ..|.:.:|         ||...|.    :|...|.......:|.|.|
  Rat   310 FRA---------------NSHKDPKDIVWFLSPVVDGLVFPE----DPVVLLTRGQVKPVPYLLG 355

  Fly   373 VTKHETANSVTVETIEKVFGSAEQFLGSLSDS---LNK--LTSFLKIDKLTGQIAKPELPGLTSV 432
            |...|             |..:..||..|..:   :||  :|..|....:...|.:.::|   .|
  Rat   356 VNSAE-------------FEWSLPFLMKLQLNQRIMNKNYITKLLWSCSILLNITEEQIP---LV 404

  Fly   433 LTPTLQDV-----WKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLA--PAFMYSFEYN 490
            ....|.|.     ||:        ..:.:::...|..| :.|.|....:.|.|  |.::|.|:::
  Rat   405 AREYLSDAISHHDWKM--------FRNHLIDLVGDATF-VYATLQAARYHRDAGSPVYLYEFKHH 460

  Fly   491 GTKSKGINFLKGLPIVSETAHDKPETVG--HGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNN 553
               :.||       ||      ||.:.|  ||||:.|:|.:....|:...|.:..|.:.:|...|
  Rat   461 ---APGI-------IV------KPRSDGADHGDELSYLFGSPFSKGSSRGEEKEFSLQMMKYWAN 509

  Fly   554 LIDL-------LVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQT 594
            ....       |..:...||||......|.:..|     :|:..|..|
  Rat   510 FAHTGDPNDRELPYWPRFDKEEKYLQLDFDTRVG-----VKLREKQMT 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	155/568 (27%)
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	155/568 (27%)