Protein Alignment CG5397 and cest-9.2

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 142/597 - (23%)
• Similarity: 234/597 - (39%)
• Gaps: 142/597 - (23%)

  Fly    74 YSFLGMHYAEPPVGPLRYSRPVY-KRLAGDFNATKHGPPCI--QPHPQFPQRIIGDEDCLLLNVY 135
            |.|..:.:|:||:|.||::.|.| ...:|..:|:|:.|.|:  ......||..: .||||.:|::
 Worm    45 YMFKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASKYSPACLSNSSTTSTPQEHV-SEDCLYINIF 108

  Fly   136 TPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQR----GAIVVAPQYRLGSLGIMGDG-TK 195
            |.:....:. ..|.|:.|.|.|...||..:....:.:|    ..|:..|..|||..|.:..| :.
 Worm   109 TSEKCLRSK-CAVIVYFHGGAYNGDSATMFPDNFILERYVAEDVILAIPGVRLGVFGQLYFGPSA 172

  Fly   196 QFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYL----SMSPTSRSAGDVHG 256
            ....||.|||...||.:|.:.|..|||:||||..:||.||......|    |:.|..:.   ...
 Worm   173 LLTENLFMFDAVQALDFVHNEIPNFGGDPKQVTIMGHSSGGTLVEALGFSNSVDPDLKL---FQQ 234

  Fly   257 VVAMSGTALSQY---AMDKEPVQSVQEVAKINGCPTG--------NELEIVNCLRSKSAEDIIKN 310
            ::.:|||.:..:   .:|...:     :::..||..|        |..||:.|:|.....:|
 Worm   235 IIVLSGTGMFGFYDLLVDNSFI-----ISEKLGCFNGTQEERTDANIAEILECMRQIDGHEI--- 291

  Fly   311 DDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRAL--PSLIVGEPEQQLKS------SNFSGI 367
                                 ||.|.|:|   |...|  .||:.|.|..:|..      ::.|..
 Worm   292 ---------------------VGMQKHME---DVYKLTFKSLLRGAPFMELNGKIEKFRNSTSPR 332

  Fly   368 PLLTGVTKHETANSV--------TVETIEKVFGSAEQFLGSLSDSLNKLTS------FLKIDKLT 418
            ..:.|.|::|..|.|        |....|.....|:.|...|..:::.:.:      |:.....:
 Worm   333 NAIFGTTEYEFRNEVERYLYITTTFLDFENPVAVAQHFDDELMQNMDTMINGDAVSIFVSAAAFS 397

  Fly   419 GQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQV-----LSKVVEST--TDVLFNLPAVLTTQVW 476
            ..:|.   .|....|..|.|  |  |.:.:|..:     :.:.|..|  .|:|.:..:.|.....
 Worm   398 SAMAN---AGADVYLFETRQ--W--PYSFHVSDMQYFIGIHREVLHTHDMDILDSFYSKLLVNFT 455

  Fly   477 SRLAPAFMYSFEYNGTKSKGINFL---------KGLPIVSETAHDKPETVGHGDEIGYMFDANDI 532
            ...||    |.|:|..:.:.:|:|         || |::.|..|||..:..:||.:.|  |.|
 Worm   456 KTGAP----SPEWNSLEPEKMNYLELRVDTRNGKG-PVMLEGYHDKEVSFWYGDMMDY--DRN-- 511

  Fly   533 FGNPMEETRLTSAEDLKVRNNLIDLLVKF------------ANKDKEEGGKSS---IFQSVT--- 579
                  .|::..::.|...|..::..:|:            ||...:|...:|   :|.|..
 Worm   512 ------ITKMRQSKGLPRENQGVESQLKYWSSIVEPRTTAHANNATQENISTSTNVLFTSTAQYI 570

  Fly   580 ----GKATPFIK 587
                ..:||.::
 Worm   571 SREFKNSTPILQ 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	142/597 (24%)
		Aes	82..>261	CDD:223730	59/190 (31%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	125/504 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810