Protein Alignment CG5397 and Ces2a

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_653344.1
• Gene: Ces2a / 246252
• RGDID: 708353
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 166/595 - (27%)
• Similarity: 250/595 - (42%)
• Gaps: 146/595 - (24%)

  Fly    11 LLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEG----FRNPST 71
            |||||.             ||.       .|..|.|:.:        ....:|.|    .::..:
  Rat    17 LLLLLQ-------------HVH-------GQDSASPIRN--------THTGQVRGSFVHVKDTKS 53

  Fly    72 GIYSFLGMHYAEPPVGPLRYSRPV-YKRLAGDFNATKHGPPCIQP---------------HPQFP 120
            ||::|||:.:|:|||||||::.|. .:..:|..:||.....|:|.               ||. |
  Rat    54 GIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQTDIMNLDGIKEMKLTVHPT-P 117

  Fly   121 QRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRGAIV-VAPQYRL 184
            .    .||||.||:|||....|.:.|||.||||.||...|||:..||:.:|....|| |:.||||
  Rat   118 M----SEDCLYLNIYTPAHAREGSNLPVMVWIHGGGLVLGSASMNDASTLAATEEIVIVSIQYRL 178

  Fly   185 GSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSR 249
            |.||....|.:...||....|..||||||...|:|||||..:|...|..:|..|.....:||.|:
  Rat   179 GVLGFFSTGDQNARGNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHVVSPMSK 243

  Fly   250 SAGDVHGVVAMSGTA-LSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDK 313
              |..||.:..||.| |.....||..| ..:.||.::||...:...::.|||:||.::|
  Rat   244 --GLFHGAIMQSGVALLPDLISDKSEV-VYKTVANLSGCEAPDSEALIRCLRAKSKQEI------ 299

  Fly   314 VQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHET 378
                 ||...:.|.:.|.|          ||:.||.    .|::.|.|.:|..:|.:.|:...|.
  Rat   300 -----LAINQVFKMIPGVV----------DGKFLPK----HPQELLASGDFHPVPSIIGINTDEC 345

  Fly   379 ANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKV 443
            ...:.|                          ||.:|.:..:|.:..||   :||..|...:...
  Rat   346 GWGIPV--------------------------FLGLDHIIKKITRETLP---TVLKSTAAQMMLP 381

  Fly   444 PQALNVDQVLSKVVESTT--------------DVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKS 494
            |:.  :|.::.:.:..|.              |.:|.:||:.........||.:.|.|::..
  Rat   382 PEC--IDLIMEEYMGDTENPETLQEQFRHMLGDFMFVIPALQVAHFQRSQAPVYFYEFQHLP--- 441

  Fly   495 KGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLIDLLV 559
               :|:|.:    ..:|.|.:   |||:|.::| .:.::|...:   ||..|:| ::..::....
  Rat   442 ---SFIKQV----RPSHVKAD---HGDDILFVF-GSYLWGMTFD---LTEEEEL-LKRRVMKYWA 491

  Fly   560 KFANKDKEEG 569
            .||......|
  Rat   492 NFARTGNPNG 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	156/558 (28%)
Ces2a	NP_653344.1	COesterase	30..537	CDD:395084	158/562 (28%)