Protein Alignment CG5397 and Ces4a

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 539
• Identity: 145/539 - (26%)
• Similarity: 232/539 - (43%)
• Gaps: 109/539 - (20%)

  Fly    71 TGIYSFLGMHYAEPPVGPLRYSRPVYK-RLAGDFNATKHGPPCIQ------------PHPQFPQR 122
            |.|..|||:.:::||||..|::.|... ...|..:||.:.|.|:|            ...|: :.
Mouse    53 TPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQY-KW 116

  Fly   123 IIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRGAIV-VAPQYRLGS 186
            :...||||.||||.|.:......|||.||...|.:..|||:.|:.:.:|.||.:| |..|||||.
Mouse   117 LHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSASTYEGSELAARGKVVLVFLQYRLGI 181

  Fly   187 LGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSA 251
            ||....|.....||..:.|..||||||.:.|..|||:|..|...|..:||.|...|.:||.::
Mouse   182 LGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQ-- 244

  Fly   252 GDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQT 316
            |..|..::.||||:.:..:..:|:.|.:::|.:.||...:...:|.||||.|||::     .:.:
Mouse   245 GLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEV-----TLVS 304

  Fly   317 ERLAGRALVKGLTGNVGFQPHIESED-----------DGRALPSLIVGEPEQQLKSSNFSGIPLL 370
            :|::            .||.:...:.           ||...|.    :|...|.......:|.|
Mouse   305 KRMS------------FFQANSHKDPKEIVWFLSPVVDGVVFPE----DPVVLLTRGQVKPVPYL 353

  Fly   371 TGVTKHETANS----VTVETIEKVFGSAEQFLGSLSDSLNK-LTSFLKIDKLTGQIAKPELPGLT 430
            .||...|...:    :.::..:::....         ::|| |.||    .:...|.|.::|
Mouse   354 LGVNNAEFEWNLPFLMKIQLNQRMMNQT---------NINKILWSF----NVLLNITKEQVP--- 402

  Fly   431 SVLTPTLQDV-----WKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLA--PAFMYSFE 488
            .|....|.|.     ||:        ..:::::...|..| :.|.|....:.|.|  |.::|.|:
Mouse   403 VVAREYLNDAISNHDWKM--------FRNRLIDLIGDATF-VYATLQAARYHRDAGSPVYLYEFK 458

  Fly   489 YNGTKSKGINFLKGLPIVSETAHDKP-ETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRN 552
            ::.  |.||       |:      || ....||||:.|      :||:|..:.. ::.|:.:...
Mouse   459 HHA--SSGI-------II------KPYNGADHGDELSY------LFGSPFSKGS-SAGEEKEFSL 501

  Fly   553 NLIDLLVKFANKDKEEGGK 571
            .::.....||:.....|.|
Mouse   502 QMMKYWANFAHTGNPNGEK 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	145/539 (27%)
		Aes	82..>261	CDD:223730	69/192 (36%)
Ces4a	NP_666325.2	COesterase	30..554	CDD:278561	145/539 (27%)
		Aes	<128..>272	CDD:223730	56/145 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910