Protein Alignment CG5397 and Ces2c

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_663578.1
• Gene: Ces2c / 234671
• MGIID: 2385905
• Length: 561
• Species: Mus musculus
• Alignment Length: 587
• Identity: 163/587 - (27%)
• Similarity: 246/587 - (41%)
• Gaps: 127/587 - (21%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEG----FRNPS 70
            |||||:              ||:     |....:|.|:.:        ....:::|    .::..
Mouse    17 LLLLLI--------------HVQ-----GQDSPEANPIRN--------THTGQIQGSLIHVKDTK 54

  Fly    71 TGIYSFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQ----------PH-----PQF 119
            .|:::|||:.:|:|||||||::.| ..:..:|..:.|.|...|:|          |.     ..|
Mouse    55 AGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSF 119

  Fly   120 PQRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPM-AQRGAIVVAPQYR 183
            |.    .||||.||:|||....|.:.|||.||||.|....|.|:.:|.:.: .....:||..|||
Mouse   120 PM----SEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVIGMASMFDGSLLTVNEDLVVVTIQYR 180

  Fly   184 LGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTS 248
            ||.||....|.:...||....|.|||||||...|::|||||.:|...|..:|..|.....:||.|
Mouse   181 LGVLGFFSTGDQHARGNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMS 245

  Fly   249 RSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDK 313
            :  |..||.:..||.||....:.:........|||::||...:...:|.|||.||..:|
Mouse   246 Q--GLFHGAIMESGVALLPDLISETSEMVSTTVAKLSGCEAMDSQALVRCLRGKSEAEI------ 302

  Fly   314 VQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGE-----PEQQLKSSNFSGIPLLTGV 373
                          |..|..|          :.:|:::.||     |::.|.|.:|..:|.:.||
Mouse   303 --------------LAINKVF----------KMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGV 343

  Fly   374 TKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQ 438
            ...|...|:.|     |.|||:...|...::|.   :.|| |.....:..||...|  ::...:.
Mouse   344 NNDEFGWSIPV-----VMGSAQMIKGITRENLQ---AVLK-DTAVQMMLPPECSDL--LMEEYMG 397

  Fly   439 DVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGL 503
            |. :..|.|.:     :..|...|.:|.:||:.........||.:.|.|::..:..|.:
Mouse   398 DT-EDAQTLQI-----QFTEMMGDFMFVIPALQVAHFQRSHAPVYFYEFQHPPSYFKDV------ 450

  Fly   504 PIVSETAHDKPETVGHGDEIGYMFDANDIFGNPM---EETRLTSAEDLKVRNNLIDLLVKFANKD 565
                ...|.|.:   |.|||.::| |:..:|..:   ||..|.|...:|...|    ..:..|.:
Mouse   451 ----RPPHVKAD---HADEIPFVF-ASFFWGMKLDFTEEEELLSRRMMKYWAN----FARHGNPN 503

  Fly   566 KE 567
            .|
Mouse   504 SE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	153/535 (29%)
		Aes	82..>261	CDD:223730	74/195 (38%)
Ces2c	NP_663578.1	COesterase	31..540	CDD:278561	155/554 (28%)
		Aes	<130..>233	CDD:223730	43/102 (42%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910