Protein Alignment CG5397 and Ces2b

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 544
• Identity: 150/544 - (27%)
• Similarity: 230/544 - (42%)
• Gaps: 102/544 - (18%)

  Fly     2 QSQLKRNTLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEG- 65
            :||: .|.|.:||..:::|.       .||:     |....:|.|:.:        ....:|.|
Mouse     3 RSQM-HNWLDVLLFGLLLLL-------GHVQ-----GQDSPEASPIRN--------THTGQVRGS 46

  Fly    66 ---FRNPSTGIYSFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQP-------HPQF 119
               .::...|:::|||:.:|:|||||||::.| ..:..:|..:.|.|...|:|.       ..:.
Mouse    47 LVHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLGVMKEIKLKL 111

  Fly   120 PQRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQ-RGAIVVAPQYR 183
            |. :...||||.||:|||....|.:.|||.||||.||...|.|:.||.:.:|. ...:||..|||
Mouse   112 PP-VSTSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGGLVAGMASMYDGSLLAAIEDLVVVTIQYR 175

  Fly   184 LGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTS 248
            ||.||....|.:...||....|..|||||:...|::|||.|.:|...|..:|..|.....:||.|
Mouse   176 LGVLGFFSTGDQHARGNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMS 240

  Fly   249 RSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDK 313
            :  |..||.:..||.||..|.:..........|||::||...:...:|.|||.||..:|:..:..
Mouse   241 K--GLFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGCEAMDSEALVRCLRGKSEAEILAINKL 303

  Fly   314 VQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGE-----PEQQLKSSNFSGIPLLTGV 373
            ||                              .:|:::.||     |::.|.|.:|..:|.:.||
Mouse   304 VQ------------------------------MIPAVVDGEFFPRHPKELLASEDFHPVPSIIGV 338

  Fly   374 TKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQ 438
            ...|..     .||..|.|||:.......::|..:     :...|.|:..|  |..:.:|.....
Mouse   339 NNDEFG-----WTIPVVMGSAQTIKEITRENLQAV-----LKNTTAQLMLP--PECSDLLMEEYM 391

  Fly   439 DVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGL 503
            ...:..|.|.:     :..|...|.:|.:||:.........|..:.|.|::.....|.:
Mouse   392 GDTEDAQTLQI-----QFTEMMEDFMFVIPALQVAYFQRSHASVYFYEFQHQIASLKDV------ 445

  Fly   504 PIVSETAHDKPETVGHGDEIGYMF 527
                ...|.|.:   |.|||.::|
Mouse   446 ----RPTHVKAD---HADEIPFVF 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	138/484 (29%)
		Aes	82..>261	CDD:223730	72/187 (39%)
Ces2b	NP_937814.1	COesterase	34..535	CDD:365897	139/500 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910