Protein Alignment CG5397 and cest-16

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 656
• Identity: 158/656 - (24%)
• Similarity: 277/656 - (42%)
• Gaps: 132/656 - (20%)

  Fly    11 LLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIYS 75
            |||||:.:.     |..:..:..|       |::..|:..::...:::.|.:         .|..
 Worm     4 LLLLLTFIF-----SWANGQLLEK-------SRSVWVEQGLVRGNIYNIDGK---------HIQI 47

  Fly    76 FLGMHYAEPPVGPLRYSRPVYK-RLAGDFNATKHGPPCIQ-----PHPQFPQRIIG--DEDCLLL 132
            |.|:.|||||:|.||:..||.| |...:..|.::||||:|     .:.:|.:..:.  .||||.|
 Worm    48 FRGVPYAEPPIGELRFKPPVKKTRWHQELPAVEYGPPCLQFMDFHKNDKFAKTNMDRQSEDCLYL 112

  Fly   133 NVYTP-QMPDETTGLPVFVWIHPGGYRYGSA-----AQYDATPMAQRGAIVVAPQYRLGSLGIM- 190
            ||::| ...||:...|:.||||.|.:..|||     .:..|..:..:|...|:..||||.||.|
 Worm   113 NVFSPYDTDDESKTYPILVWIHGGSFLAGSADTGIDMEVIAANIVSKGIAFVSINYRLGPLGFMN 177

  Fly   191 ---GDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAG 252
               ||   :.:||..::|:..||:|:...|..|.|:|.:|..:|..:|.|::..|::||  :::|
 Worm   178 YQNGD---KLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLLALSP--KTSG 237

  Fly   253 DVHGVVAMSGTALSQYAMDK--EPVQSVQEVAKINGCP-----------TGNELE---------- 294
            .:|..:.|||::::.:|:.:  :|..||..:.....|.           .|:|.:
 Worm   238 LLHQAIIMSGSSMAGWAIHRHSQPAYSVDNLVAYFRCEKWINEDDTKEVVGDEYQHLTHSVIRSA 302

  Fly   295 -------IVNCLRSKSAEDIIKNDDKVQTERL---------AGRALVKGLTGNVGFQPHIESEDD 343
                   .:|||          .||..|.:::         :.....|.|...:|....:.   |
 Worm   303 LCNYQNVKINCL----------TDDMTQMDKMNCLRKELNFSSPLFRKALAAELGVSKMVV---D 354

  Fly   344 GRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKL 408
            |..:||..|     .|..:| :.||::|||.:.|..:.      :.:|.:..|..|.....:.:.
 Worm   355 GDLVPSSGV-----SLVRNN-ARIPIMTGVARKEWGHK------KAMFYNMHQRDGLKRSDVEEQ 407

  Fly   409 TSFLKIDKLTGQIAKPELPGLT--SVLTPTLQDVWKVP-QALNVDQVLSKVVESTTDVLFNLPAV 470
            . :..||....:.|..:|...|  .:...|:....:.| .....|||:..:.:..:|:.|..|..
 Worm   408 V-YRIIDNSFHETASEKLANSTVQLIANATIVRYLETPNNEFIADQVVGALQKLESDIEFVAPCE 471

  Fly   471 LTTQVW-SRLAPAFMYSFEYNGTKS------KGINFLKGLPIVSETAHDKPETVG----HGDEIG 524
            .....: .:..|.::|||:| ..||      :.|..|.|...|.....:|.|.:.    ||.:..
 Worm   472 REVAAYVDKGVPVYLYSFDY-VPKSPILESERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDHA 535

  Fly   525 YMFDANDIFGNPMEETRLTSAEDLKVRNNLIDLLVKFANKDKEEGGKSS--IFQSVTGKATPFIK 587
            ::|...  :.:..|.:..|..|: .:...|..:|..|.........:.|  ||   :|.::.::.
 Worm   536 FIFSKG--YSSNFEISPYTKREE-TMSKILCTMLTNFVKNGDPSTTRFSWPIF---SGNSSQYVS 594

  Fly   588 IDTKLQ 593
            :|..|:
 Worm   595 LDVPLK 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	149/619 (24%)
cest-16	NP_741812.2	alpha/beta hydrolases	23..608	CDD:473884	151/625 (24%)