Protein Alignment CG5397 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 124/488 - (25%)
• Similarity: 199/488 - (40%)
• Gaps: 92/488 - (18%)

  Fly    66 FRNPSTGIYSFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQPHPQ-FPQRIIG--- 125
            |.|.|.  .:|||:.|.|||:|.||:.:| ..|..:|.....|..|.|:....: :....||
 Worm    40 FGNQSA--IAFLGIPYVEPPIGDLRFRKPRPQKTWSGVLETKKFKPACMSNSTKTYKNGGIGGPI 102

  Fly   126 DEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMA------QRGAIVVAPQYRL 184
            .||||.|||.|.|...|.....|.:.:|.|||.:.|||.::...:.      .|..:||...|||
 Worm   103 SEDCLYLNVLTNQYCLENKNCSVVIIVHGGGYLFESAATFNHEILVNNFVGQDRNIVVVTINYRL 167

  Fly   185 GSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSR 249
            |..|.......:.|.|:.:||...|::||...|..||||..::...||.:||......::||.::
 Worm   168 GIFGFGHLNGFEGDKNVGIFDTLEAVKWVRREIKQFGGNKDRITLAGHSAGAGVVAAFTISPLTK 232

  Fly   250 SAGDVHGVVAMSG--TALSQYAMDKEPVQSVQEVAKINGC----------PTGNELEIVNCLRSK 302
              |.:|..:.|||  |.:|:    |...:.:..:|:..||          |.....::.:|||.|
 Worm   233 --GLIHQQIVMSGPMTNMSK----KSNFKGMTAMAERVGCHSKKYGFNKLPEHEVEQVYSCLRKK 291

  Fly   303 SAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGI 367
            .|::::.          |...|::..|...| .|.::.|        .|...|:......:...|
 Worm   292 PAQELLD----------AQLWLLQNSTFYFG-APPVDGE--------FITDYPDNLYSEKSIFSI 337

  Fly   368 PLLTGVTKHETANS--VTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLT 430
            ..|.|.|..|..::  ::.....| |.:.|.||.:|.|.:. :..:.:.:..:.:..|..:.|..
 Worm   338 NTLLGTTTRELQDTGYISNSNYSK-FETKETFLKNLCDQIG-IEIYKESEDFSSKCQKWYINGSD 400

  Fly   431 SVLTPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLA-PAFMYSFEYNGTKS 494
            |   .:|.|                      |:.|...|:......:|.. ..:|||:.|:|.
 Worm   401 S---KSLSD----------------------DMEFYTQAINLADAHARKGKKVYMYSYAYSGA-- 438

  Fly   495 KGINFLKGLPIVSETAHDKPETVGHGDEIGYMF 527
             |..|.|.:.:.|      |.   |.:::.|.|
 Worm   439 -GPAFKKYMKVKS------PH---HSEDLIYTF 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	124/488 (25%)
		Aes	82..>261	CDD:223730	60/189 (32%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	124/488 (25%)
		Aes	<125..>250	CDD:223730	40/126 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910