Protein Alignment CG5397 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 146/642 - (22%)
• Similarity: 223/642 - (34%)
• Gaps: 205/642 - (31%)

  Fly    37 VGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTG-------------IYSFLGMHYAEPPVGP 88
            :||..|...|..:..:|              |.|.|             :..:||:.:|:.|:|.
 Worm     1 MGGFLSHLKPEKNTEVF--------------NASCGPIRGNVYEHGDKIVNGYLGIPFAKAPIGD 51

  Fly    89 LRYSRPV-YKRLAGDFNATKHGPPCIQPH-------PQFPQRIIGDEDCLLLNVYTP-----QMP 140
            ||:.:.| .::.....:..|:||.|.|..       .|.......:::||.|||:.|     :.|
 Worm    52 LRFKKSVEAEKWTQPLDCYKYGPGCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFP 116

  Fly   141 DETTGLPVFVWIHPGGYRYGSAAQYD------ATPMAQRGAIVVAPQYRLGSLGIMGDGTKQFDG 199
            :   |.||.|:.:.||:..|.::.:|      ..|:  :..|:|.|.||:|.||....|.....|
 Worm   117 N---GFPVMVYFYGGGFEVGFSSMFDDYSLTGTLPL--KDVILVTPNYRIGPLGFFATGDDVARG 176

  Fly   200 NLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTA 264
            |..::|.|.||:||..:|..|||:|..|...|..:|.||..:||:||.:...  ....:.|||.|
 Worm   177 NWGLWDQALALQWVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKY--FQKFIPMSGAA 239

  Fly   265 LSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLT 329
            .                     ||.|        :|||..|.:|..:          .|...|.|
 Worm   240 T---------------------CPFG--------IRSKDVEGLIFRE----------FANHHGYT 265

  Fly   330 GN--VGFQPHIESED-------DGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVE 385
            ||  .......:|:|       :|...|:           |..||.:|...|
 Worm   266 GNDSKSLLQWYQSQDSEIFLKAEGYKCPA-----------SGMFSFVPNFDG------------- 306

  Fly   386 TIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVW---KVPQAL 447
                      .|.....|.|.|     :..||...::..|..||      ..:|.:   |.||.:
 Worm   307 ----------DFFPKPFDELRK-----EAPKLGAIVSIGEYEGL------GFEDFYAGQKTPQQM 350

  Fly   448 -------------------------------NVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLA- 480
                                           |.:.:...:||...|..|::.|..|.:...:..
 Worm   351 LSAALGPEVVRNREEVVKRAAESYLKNGGNENEENIAKTLVEIFGDYYFSVGAFDTVRSLVKYGN 415

  Fly   481 PAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKP-ETVGHGDEIGYMFDANDIFGNPMEETRLTS 544
            ..::|||.|         |....|||  ...::| ....||.::.|      |||   |.|...|
 Worm   416 TVYLYSFNY---------FNPNTPIV--FGKNRPFNAANHGSDLRY------IFG---EGTGEFS 460

  Fly   545 AEDLKVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATP--FIKID-TKLQTSNDF 598
            .||.:|.:.:......||......|...|:.........|  :.||| .|.:.:::|
 Worm   461 KEDRQVMDMMGTYHTNFAKYGNPNGKGVSVPWEKYSLDNPGRYFKIDYPKCEMADNF 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	141/617 (23%)
		Aes	82..>261	CDD:223730	59/197 (30%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	141/625 (23%)
		Aes	<105..>239	CDD:223730	46/140 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900