Protein Alignment CG5397 and cest-32

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 136/575 - (23%)
• Similarity: 239/575 - (41%)
• Gaps: 125/575 - (21%)

  Fly    66 FRNPSTGIYSFLGMHYAEPPVGPLRYSRPV-YKRLAGDFNATKHGPPCIQPHPQFPQ------RI 123
            :|:....:..:||:.:|:.|:..||:.:|| .::.....|..|:||.|.|.......      |.
 Worm    29 YRHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKYGPGCPQSGHMISNLLPPGYRE 93

  Fly   124 IGDEDCLLLNVYTPQMPDE--TTGLPVFVWIHPGGYRYGSAAQYD----ATPMAQRGAIVVAPQY 182
            ..:::||.||::.|....|  ..|||:.|:.|.||:..|.::.:|    :..:..:..|||...|
 Worm    94 FAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIGFSSMFDDYSLSGTLPLKDVIVVTANY 158

  Fly   183 RLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPT 247
            |:|.||.|..|.:...||..::|...||:||.::|..|||||..|...|..:|..||..|::||.
 Worm   159 RVGPLGFMTTGDEVSRGNYGLWDQTLALKWVQEHIKSFGGNPNIVTVCGTSAGGVSAGLLALSPH 223

  Fly   248 SRSAGDVHGVVAMSGTALSQYAM--DKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKN 310
            |...  .|..:||||:|..::::  .::..:..:..||.:|. .|.:.|  :.|....::.:.|.
 Worm   224 SNKL--FHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGY-EGEDSE--SLLEWYKSQPLSKF 283

  Fly   311 DDKVQTERLAGRALVKGLTGNVGFQPHIESE------DD-GRALPSLIVGEPEQQLKSSNFSGIP 368
            .:....|:.|        :|.:.|.|:.:.:      |: .|..|.|     :.......:.|:.
 Worm   284 QETATFEKKA--------SGFLTFIPNFDGDFFPKPFDELSREAPKL-----DAMATVDEYEGLG 335

  Fly   369 LLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFL--KIDKLTGQIAKPELPGLTS 431
            .||.......    .::.|:..|||  ..:.:..|...::..|.  .|||
 Worm   336 FLTMFQSRRN----DMDIIKSSFGS--DVVENAVDVQKRIMEFYMKNIDK--------------- 379

  Fly   432 VLTPTLQDVWKVPQALNVDQVLSK-VVESTTDVLFNLPAVLTTQVWSRL-APAFMYSFEYNGTKS 494
                            |.|:.:.| :::..:|..||:.|:.|.:..::. :.|::.||:|   .:
 Worm   380 ----------------NDDKAVEKRLIQLISDSWFNIGALETVKTSTKYGSNAYLGSFDY---YN 425

  Fly   495 KGIN--FLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLIDL 557
            .|.|  :....|.         :...||.|:.||........:|:|       |:.||    ||:
 Worm   426 MGSNDPYATWFPF---------KAANHGSELKYMLGEGMGKFSPIE-------EEFKV----IDM 470

  Fly   558 L-------VKFANKDKEEGGKSSIFQSVTGKATP-----FIKID-TKLQTSNDFR 599
            :       ||:.|.:...|      ..:..|.||     :.||| .|.:..::|:
 Worm   471 MGTLTANFVKYGNPNGING------PELWKKYTPEKPYSYFKIDYPKSEMRDNFQ 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	135/573 (24%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	135/573 (24%)