Protein Alignment CG5397 and cest-25

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 144/537 - (26%)
• Similarity: 215/537 - (40%)
• Gaps: 100/537 - (18%)

  Fly    63 VEGFRNPSTG---IYSFLGMHYAEPPVGPLRYSRPVYKRLAGDFNATK-HGPPCIQ-PHPQFPQR 122
            :||.|....|   :.:|.|:.||.||:|.||::.|.......:...|| .|...|| .|...|:.
 Worm    26 IEGRRLIHEGEKQVDAFQGIPYAAPPIGNLRFALPQPHEKWTEVRETKSFGARGIQKDHVLSPKT 90

  Fly   123 IIGDEDCLLLNVYTP-QMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQ----RGAIVVAPQY 182
            ....||.|.||::|| ..|...||.||.::||.||:...||.:|....:.|    :..:||..||
 Worm    91 SPQSEDNLTLNIFTPVWTPKNETGFPVILYIHGGGFVSDSAHKYGDMSICQHLVTKDVVVVTIQY 155

  Fly   183 RLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPT 247
            |||.||....|......|:|:.|:..||:||.:.|..|.|:|..:..:|..:|.||..:||:||.
 Worm   156 RLGFLGFWTTGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPV 220

  Fly   248 SRSAGDVHGVVAMSGTALSQYAMDKEPVQS----VQEVAKINGCPTGNELEIVNCLRS------K 302
            ||..  ...|:.|.|.|...:|:...|:.:    .||:...:|.   |.|:.|..||.      .
 Worm   221 SRDL--FQKVIPMGGNASCSWAIHPRPLNACRNRAQEIGVFDGM---NTLDWVEKLRELPADKFA 280

  Fly   303 SAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQL-KSSNFSG 366
            ||.::...|.|...|.|.|              |..:         :|.:..|..:| |.:...
 Worm   281 SALNMEAVDTKTDPELLIG--------------PKYD---------NLFIPRPVMELRKEAPMK- 321

  Fly   367 IPLLTGVTKHETANSVTVETIEKVFG-SAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLT 430
             |.|.|..|.|       ..:...|| :.:..|.::...::.:.|............:..|..|.
 Worm   322 -PRLLGCAKSE-------GLVFAFFGLNTKHPLHAVQQDVSAILSEKLFPLKARDYQEKALEKLI 378

  Fly   431 SVLTPTLQDVW-------KVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFE 488
            .:.|...::.|       |....|||.     :.::..|||...|:          .|.:||||:
 Worm   379 EIGTDHSKEEWQRAMVDLKGDSFLNVG-----IQQNVLDVLETQPS----------TPIYMYSFD 428

  Fly   489 YNGTKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLK---V 550
            |...|:.||...| ||....|         |..:|.|      :.||.:..:...:.||.|   :
 Worm   429 YCNPKAYGIMGFK-LPFKDAT---------HCTDISY------VVGNHIVNSFDFNEEDYKMIEI 477

  Fly   551 RNNLIDLLVKFANKDKE 567
            ...|.....|:.|.:.|
 Worm   478 TTRLWTNFAKYGNPNGE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	144/537 (27%)
		Aes	82..>261	CDD:223730	66/185 (36%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	144/537 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810