Protein Alignment CG5397 and Nlgn3

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 161/607 - (26%)
• Similarity: 249/607 - (41%)
• Gaps: 174/607 - (28%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPST--- 71
            |:|..||:|:.||                 .|:.||.|:  ..|.:|  |.|||.   .||.
  Rat    24 LILWFLSLVLRAS-----------------TQAPAPTVN--THFGKL--RGARVP---LPSEILG 64

  Fly    72 GIYSFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQP-HPQFPQRII---------- 124
            .:..:||:.||.||:|..|:..| .....:|..|||...|.|.|. |...|:.::
  Rat    65 PVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDI 129

  Fly   125 -------GDEDCLLLNVYTP------------QMP------------------------DETTGL 146
                   .:||||.||||.|            :.|                        ||...:
  Rat   130 VATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDI 194

  Fly   147 ------PVFVWIHPGGYRYGSAAQYDATPMAQRG-AIVVAPQYRLGSLGIMGDGTKQFDGNLAMF 204
                  ||.|:||.|.|..|:....|.:.:|..| .||:...||:|.||.:..|.:...||..:.
  Rat   195 RDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 259

  Fly   205 DLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTALSQYA 269
            |...|||||::.|::|||:|:::...|.|.||:....|::|  ..|.|.....:..||:|||.:|
  Rat   260 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS--HHSEGLFQRAIIQSGSALSSWA 322

  Fly   270 MDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGF 334
            ::.:||:....:|...||...:.:::|:|||.|||:::::.|  :|..|.           :|.|
  Rat   323 VNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQD--IQPARY-----------HVAF 374

  Fly   335 QPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSV--TVETIEKVFG----- 392
            .|.|    ||..:|.    :||..::...|....::.||.:.|....|  .|:..:.|.|
  Rat   375 GPVI----DGDVIPD----DPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 431

  Fly   393 SAEQFLGSL------SDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQ 451
            |...|:.:|      .|:|.:...|:..|                         |  ....|.:.
  Rat   432 SVSNFVDNLYGYPEGKDTLRETIKFMYTD-------------------------W--ADRDNPET 469

  Fly   452 VLSKVVESTTDVLFNLPAVLTTQVWSRL-APAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPE 515
            ....:|...||..:..|:|:|..:.:|. :|.:.|:| |:..:|    .:|  |..|:.|
  Rat   470 RRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAF-YHHCQS----LMK--PAWSDAA----- 522

  Fly   516 TVGHGDEIGYMFDANDIFGNPM 537
               ||||:.|      :||.||
  Rat   523 ---HGDEVPY------VFGVPM 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	150/569 (26%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	153/574 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		2/25 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691