Protein Alignment CG5397 and Ces1e

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 589
• Identity: 168/589 - (28%)
• Similarity: 257/589 - (43%)
• Gaps: 108/589 - (18%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIY 74
            :.|..|.:|.||:..:|           .|..|..|.||  .:..::..:...:|||..|   :.
Mouse     1 MCLSALILVSLAAFTAG-----------AGHPSSPPMVD--TVQGKVLGKYISLEGFTQP---VA 49

  Fly    75 SFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQPHPQFPQRIIGD------------ 126
            .|||:.:|:||:|.||::.| ..:..:...|||.:.|.|.| .|...| |:.|
Mouse    50 VFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQ-DPVTGQ-IVNDLLTNRKEKIPLQ 112

  Fly   127 --EDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMA-QRGAIVVAPQYRLGSLG 188
              ||||.||:|||....::..|||.||||.||...|.|:.||...:: ....:||..|||||..|
Mouse   113 FSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLGGASTYDGLVLSTHENVVVVVIQYRLGIWG 177

  Fly   189 IMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGD 253
            ....|.:...||....|..|||.||.|.|:.|||:|..|...|..:|..|...|.:||.:::.
Mouse   178 FFSTGDEHSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNL-- 240

  Fly   254 VHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTER 318
            ....::.||.||:...:.|......:::|.|:||.......:|:|||.|:.|:::....|:...:
Mouse   241 FQRAISESGVALTAGLVKKNTRPLAEKIAVISGCKNTTSAAMVHCLRQKTEEELLGTTLKLNLFK 305

  Fly   319 LAGRALVKGLTGNV-GFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSV 382
            |       .|.|:. ...|.:.:..||..||.:    ||:.|...||:.:|.:.|:.|.|
Mouse   306 L-------DLHGDSRQSHPFVPTVLDGVLLPKM----PEEILAEKNFNTVPYIVGINKQE----- 354

  Fly   383 TVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQ---------IAKPELPGLTSVLTPTLQ 438
                    ||      ..|...:|...|.:|:|::|..         :..|| ..:...:...|:
Mouse   355 --------FG------WILPTMMNYPPSDVKLDQMTAMSLLKKSSFLLNLPE-DAIAVAIEKYLR 404

  Fly   439 DVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRL-APAFMYSFEYNGTKSKGINFLKG 502
            |  |.....|.||:|    |...||:|.:|:|:.::..... ||.:||.|:|:.:.|..:
Mouse   405 D--KDYTGRNKDQLL----ELIGDVVFGVPSVIVSRGHRDAGAPTYMYEFQYSPSFSSEM----- 458

  Fly   503 LPIVSETAHDKPETV--GHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLIDLLVKFANKD 565
                      ||:||  .|||||..:|.|..:.|.       ||.|::.:...::.....||...
Mouse   459 ----------KPDTVVGDHGDEIYSVFGAPILRGG-------TSEEEINLSKMMMKFWANFARNG 506

  Fly   566 KEEG 569
            ...|
Mouse   507 NPNG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	157/537 (29%)
		Aes	82..>261	CDD:223730	69/194 (36%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	160/554 (29%)
		Aes	44..>242	CDD:223730	74/204 (36%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910