Protein Alignment CG5397 and Nlgn1

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 157/648 - (24%)
• Similarity: 249/648 - (38%)
• Gaps: 177/648 - (27%)

  Fly    49 DPVIFARLFDRDARVEGFR----NPSTG-IYSFLGMHYAEPPVGPLRYSRPVYKRLAGDF-NATK 107
            ||::....    .::.|.:    |...| :..|||:.||.||.|..|:..|.......|. |||:
  Rat    52 DPLVTTNF----GKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQ 112

  Fly   108 HGPPCIQPHPQFPQRIIG--------------------------DEDCLLLNVYTP--------- 137
            ..|.|       ||.||.                          .||||.||:|.|
  Rat   113 FAPVC-------PQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISK 170

  Fly   138 ----------------------------------QMPDETTGLPVFVWIHPGGYRYGSAAQYDAT 168
                                              .:.|.....||.|:||.|.|..|:...||.:
  Rat   171 ECARKPGKKICRKGGPLTKTQTDDLGDNDRAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGS 235

  Fly   169 PMAQRG-AIVVAPQYRLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGH 232
            .:|..| .||:...||||.||.:..|.:...||..:.||..||||.::.|.:|||:|.::...|.
  Rat   236 VLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGS 300

  Fly   233 GSGAASAMYLSMSPTS---RSAGDVHGV----VAMSGTALSQYAMDKEPVQSVQEVAKINGCPTG 290
            |:|.:....|::|..|   |.:....|:    :|.||||||.:|:..:|.:..:.:|...||...
  Rat   301 GAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVS 365

  Fly   291 NELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEP 355
            :.:|:|.||:.|..::::  |..||..|.           ::.|.|.|    ||..:|.    :|
  Rat   366 DTVELVECLQKKPYKELV--DQDVQPARY-----------HIAFGPVI----DGDVIPD----DP 409

  Fly   356 EQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQ 420
            :..::...|....::.||.:.|     .::.:|.:..|.:..  |.||....:::|  :|.|.|
  Rat   410 QILMEQGEFLNYDIMLGVNQGE-----GLKFVENIVDSDDGV--SASDFDFAVSNF--VDNLYG- 464

  Fly   421 IAKPELPGLTSVLTPTLQDV---WKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRL-AP 481
                 .|....||..|::.:   |  ....|.:.....::...||..:..|||.|..:.|.. :|
  Rat   465 -----YPEGKDVLRETIKFMYTDW--ADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSP 522

  Fly   482 AFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPM-EETRL--- 542
            .:.|:|.::....:       :|..::.|        ||||:.|      :.|.|| ..|.|
  Rat   523 TYFYAFYHHCQTDQ-------VPAWADAA--------HGDEVPY------VLGIPMIGPTELFPC 566

  Fly   543 -TSAEDLKVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRFCELS 604
             .|..|:.:...::.....||.               ||.....:..|||...:...||.|::
  Rat   567 NFSKNDVMLSAVVMTYWTNFAK---------------TGDPNQPVPQDTKFIHTKPNRFEEVA 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	154/641 (24%)
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	157/648 (24%)